Results 71 to 80 of about 78,339 (310)
Advanced Science, EarlyView.Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang +12 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Autoinflammatory disorders (AIDs) are a clinically heterogeneous group of inborn errors of immunity primarily caused by dysregulation in the innate immune system. Clinical diagnosis is often challenging due to clinical heterogeneity and the overlapping phenotypes with other inborn errors of immunity and monogenic conditions that mimic AIDs ...
Vaishnavi Ashok Badiger +28 more
wiley +1 more source
American Journal of Ophthalmology Case Reports, 2019 Purpose: To report a case of bilateral acute necrotising retinitis due to cytomegalovirus infection (CMV) in an Asian Indian infant. Observations: An Asian Indian infant born with a birth weight of 1000 g at 26 week of gestation acquired cytomegalovirus ...
Padmamalini Mahendradas +4 more
doaj +1 more source
Real-Life Data on the Efficacy of Canakinumab in Patients with Adult-Onset Still’s Disease
Mediators of Inflammation, 2020 Background. Interleukin-1 inhibition has revealed to be a successful treatment approach for patients with adult-onset Still’s disease (AOSD). However, real-life experience is focused on the use of anakinra, while data about canakinumab (CAN) are mainly ...
Antonio Vitale +12 more
doaj +1 more source
Clinical patterns and characteristics of uveitis in a secondary hospital in southern China [PDF]
International Journal of Ophthalmology, 2015 AIM: To investigate the characteristics of uveitis in a secondary hospital in southern China. METHODS: We reviewed all records of patients with uveitis at Hengli Hospital from January 2008 to December 2011.
Yang Zheng +7 more
doaj +1 more source
Journal of Applied Polymer Science, EarlyView.PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski +6 more
wiley +1 more source
International Journal of Inflammation, 2012 Chronic postoperative endophthalmitis (CPE) is a delayed infectious intraocular inflammation process that occurs more than six weeks after ocular surgery and frequently masquerades as autoimmune uveitis.
Fadi Maalouf +2 more
doaj +1 more source
JAMA: The Journal of the American Medical Association, 1902 Properly speaking, the term uveitis should be applied to an inflammation of any portion of the uveal tract which embraces iris, ciliary body and choroid; and an inflammatory process in any one of these structures, if severe and protracted, may involve the other divisions.
openaire +1 more source
Arthritis &Rheumatology, EarlyView.Objective To compare the multisequence standard magnetic resonance imaging (sMRI) protocol of the sacroiliac joints with a single high‐resolution deep learning–reconstructed Dixon sequence (DL‐Dixon) in patients with suspected axial spondyloarthritis (axSpA). Methods Seventy‐six patients with chronic low back pain and suspected axSpA underwent clinical,
Dominik Deppe +12 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective The purpose of this study was to estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axial spondyloarthritis (axSpA) and to identify factors associated with D2M and TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis ...
Patricia Remalante‐Rayco +8 more
wiley +1 more source