Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Inspección visual de tramos de vía en el sector de Pinares, ubicados entre las calles novena, diez y once, con carreras dieciocho, diecinueve y veinte de la ciudad de Pereira, Risaralda [PDF]
La finalidad del presente trabajo es realizar la inspección visual de los tramos de vía comprendidos entre las calles novena (9), diez (10) y once (11), con carreras dieciocho (18), diecinueve (19) y veinte (20), sector conocido con el nombre de Pinares ...
Guarín Gómez, Estefanía +3 more
core +1 more source
Data-Driven Precision Harvest Planning via Visual Growth Forecasting
While Artificial Intelligence (AI) techniques have been widely applied to problem-solving, their true transformative power lies in enhancing people’s practice.
Junhan Wen +2 more
doaj +1 more source
Study of the application of negative pressure suctioning via visual suction tube for oral secretion removal in patients with post-stroke dysphagia [PDF]
Objective To evaluate the effect of negative pressure suctioning via visual suction tube on the removal of oral secretions in patients with post-stroke dysphagia (PSD).
CHEN Qiongmei, LI Yuanfang, WU Xiulan, CHEN Yurong, WEN Hongmei, DOU Zulin
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
When Drift becomes Current: Collaborating to Expand Beyond the Visual [PDF]
In 2015, SUNY Purchase College art librarian Kim Detterbeck reimagined a long-standing part-time Visual Resources position into a full-time Digital Collections Curator position.
Oliver, Mēgan, Detterbeck, Kimberly
core
2021 State of the Visual Resources Association Address [PDF]
During the remote 2021 Annual Business Meeting at the Annual Conference of the Visual Resources Association, the president highlighted the accomplishments and challenges of the Association in a state of the association presentation. This article provides
Keefer, Jeannine
core
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Symbiotic brain-machine drawing via visual brain-computer interfaces
Brain-computer interfaces (BCIs) are evolving from research prototypes into clinical, assistive, and performance enhancement technologies. Despite the rapid rise and promise of implantable technologies, there is a need for better and more capable ...
Gao Wang +3 more
doaj +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source

