Results 21 to 30 of about 1,886,665 (203)

Exposure of domestic animals to Mayaro and Oropouche viruses in urban and peri-urban areas of West-Central Brazil

One Health Outlook
Oropouche and Mayaro viruses are enzootic arboviruses of public health concern throughout Latin America. Recent outbreaks of OROV in northern region and sporadic autochthonous cases in western region of Brazil, suggest a silent circulation of these ...
Helver Gonçalves Dias, Débora Familiar-Macedo, Ingrid Oliveira Garrido, Flávia Barreto dos Santos, Alex Pauvolid-Corrêa   +4 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

In-depth analysis of the replication cycle of Orpheovirus

Virology Journal, 2019
Background After the isolation of Acanthamoeba polyphaga mimivirus (APMV), the study and search for new giant viruses has been intensified. Most giant viruses are associated with free-living amoebae of the genus Acanthamoeba; however other giant viruses ...
Fernanda Souza, Rodrigo Rodrigues, Erik Reis, Maurício Lima, Bernard La Scola, Jônatas Abrahão   +5 more
doaj   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

Erradicação da doença de Aujeszky em Santa Catarina: importância da condição sanitária das leitoas de reposição Aujeszky's diasease eradication in Santa Catarina State: relevance of sanitary status of replacement gilts

Ciência Rural, 2008
A doença de Aujeszky (DA) é uma infecção causada por um herpesvírus, o vírus da DA (VDA), primariamente em suínos. Esta doença está presente no Estado de Santa Catarina (SC) desde 1984.
Janice Reis Ciacci-Zanella, Armando Lopes do Amaral, Lauren das Virgens Ventura, Nelson Morés, Hélio Bortoluzzi   +4 more
doaj   +1 more source

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna, Alexia Muresan, Estelle Lecluze, Karine Leduc, Nathalie Fournier, Maria Tamer, Jean‐François Delisle, Jeremi Charbonneau, Annie Viau, Jessica Darilus, Marie‐Joëlle Doré‐Bergeron, Valérie Arsenault, Evelyne Doyon‐Trottier, Stéphanie Forte, Nancy Robitaille, Yves Pastore, Thomas Pincez   +16 more
wiley   +1 more source

Revealing the hidden diversity of Chlorella heliozoae-infecting giant viruses

npj Viruses
A new level of viral complexity has emerged from the isolation of green algae-infecting chloroviruses from diverse aquatic environments around the world over the past few decades.
Lethícia R. Henriques, Bruna B. F. Botelho, Roger M. Carlson, João Victor R. P. Carvalho, Ellen G. Oliveira, Irina V. Agarkova, James L. Van Etten, David D. Dunigan, Rodrigo A. L. Rodrigues   +8 more
doaj   +1 more source

Zoonotic transmission of novel Influenza A variant viruses detected in Brazil during 2020 to 2023

Nature Communications
Zoonotic infections (swine-human) caused by influenza A viruses (IAVs) have been reported and linked to close contact between these species. Here, we describe eight human IAV variant infections (6 mild and 2 severe cases, including 1 death) detected in ...
Paola Cristina Resende, Dennis M. Junqueira, Caroline Tochetto, Maria Ogrzewalska, Fernando C. Motta, Jonathan Lopes, Luciana Appolinario, Larissa Macedo, Braulia Caetano, Aline Matos, Thauane Silva, Elisa Cavalcante Pereira, Leticia Ferreira Lima, Irina Riediger, Maria do Carmo Debur, Guilherme Nardi Becker, Aline Andrade, Acácia Maria Lourenço Francisco Nasr, Rosana Aparecida Piler, Ana Carolina Dalla Vecchia, Walquíria Almeida, David Brown, Rejane Schaefer, Marilda M. Siqueira   +23 more
doaj   +1 more source

Seroconversion and seroreactivity patterns of dairy goats naturally exposed to caprine arthritis-encephalitis virus in Brazil Soroconversão e sororeatividade de cabras leiteiras naturalmente expostas ao virus da artrite-encefalite caprina no Brasil

Ciência Rural, 2002
A labelled avidin-biotin ELISA (lab-ELISA) using repeated serum samples of goats showed a progressive seroconversion with higher seroconversion rate at the period going from the beginning of the breeding up to the last half of lactation (35.0%), compared
Roberto Soares Castro, Rômulo Cerqueira Leite, Edisio Oliveira de Azevedo, Maurício Resende, Aurora Maria Guimarães Gouveia   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source