Results 31 to 40 of about 1,886,665 (203)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

DEVIR COM OS VÍRUS NO ANTROPOCENO

Revista da SBEnBIO
Buscamos, neste artigo, apresentar modos como a existência dos vírus pode afetar a divulgação científica, tangenciando diálogos com a educação e o ensino de ciências e biologia.
Tiago Amaral Sales, Susana Oliveira Dias
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Bactériofagos como nanocarreadores de fármacos no tratamento do câncer: protocolo de Revisão de Escopo

Cadernos Cajuína
O tratamento convencional do câncer apresenta limitações importantes, uma vez que muitas terapias antineoplásicas atuam de forma não seletiva. Esse mecanismo contribui para o desenvolvimento de efeitos adversos, toxicidade sistêmica e comprometimento da
Lara Cardoso Guimarães Aires, Flávio Monteiro Ayres, Jaqueline Gleice Aparecida de Freitas   +2 more
doaj   +1 more source

Disseminação do vírus da doença de Aujeszky, envolvendo o comércio de reprodutores suínos de reposição Spread of virus of Aujeszky's disease by the trade of replacement swine breeders

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
Relata-se a disseminação da infeção pelo vírus da doença de Aujeszky (VDA) a partir da comercialização de reprodutores suínos oriundos de duas granjas de reprodutores suídeos certificada (GRSC) que tiveram surto da DA.
N. Mores, A.L. Amaral, L. Ventura, J.R.C. Zanella, A. Mori, J.A. Dambrós, G. Provenzano, I. Bisolo   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Infecção viral da vinha nos Biscoitos (ilha Terceira) - Açores Grapevine virus infection at Biscoitos (Terceira island) - Azores

Revista de Ciências Agrárias, 2009
A região dos Biscoitos na ilha Terceira, nos Açores, é mundialmente conhecida pela vinha em curraletas destinada à produção de Vinhos Licorosos de Qualidade Produzidos em Região Demarcada (VLQPRD).
Arícia Figueiredo, Isabel Cortez, Ana Maria Nazaré Pereira   +2 more
doaj  

Dengue virus 3 genotype I (GI) lineage 1 (L1) isolates elicit differential cytopathic effect with syncytium formation in human glioblastoma cells (U251)

Virology Journal, 2023
Background Dengue virus (DENV) is a Flaviviridae member classified into four antigenically distinct serotypes (DENV 1, 2, 3, and 4) and further subdivided genotypes. DENV3 is subdivided into four or five genotypes, depending on the classification adopted.
Adriana de Souza Andrade, Sofia Oliveira Campos, Jamile Dias, Marco Antônio Campos, Erna Geessien Kroon   +4 more
doaj   +1 more source