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A doença de Aujeszky (DA) é uma infecção causada por um herpesvírus, o vírus da DA (VDA), primariamente em suínos. Esta doença está presente no Estado de Santa Catarina (SC) desde 1984.
Janice Reis Ciacci-Zanella +4 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Revealing the hidden diversity of Chlorella heliozoae-infecting giant viruses
A new level of viral complexity has emerged from the isolation of green algae-infecting chloroviruses from diverse aquatic environments around the world over the past few decades.
Lethícia R. Henriques +8 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A labelled avidin-biotin ELISA (lab-ELISA) using repeated serum samples of goats showed a progressive seroconversion with higher seroconversion rate at the period going from the beginning of the breeding up to the last half of lactation (35.0%), compared
Roberto Soares Castro +4 more
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The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Clonagem e expressão de um fragmento recombinante da proteína de 28 KDa do vírus da síndrome da mancha branca (WSSV) de camarões [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia, Florianópolis, 2009O vírus da síndrome da mancha branca (WSSV) é o agente infeccioso que trouxe maiores prejuízos ...
Braünig, Patrícia
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Análise filoginética e genotipagem de amostras de vírus rábico através da técnica de seqüênciamento automatizado de produtos de RT-PCR [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina. Programa de Pós-Graduação em Biotecnologia.O vírus rábico pertence à Ordem Mononegavirales e Família Rhabdoviridae, sendo constituído por um RNA de sentido negativo, não-segmentado e que ...
Bordignon, Juliano
core
DEVIR COM OS VÍRUS NO ANTROPOCENO
Buscamos, neste artigo, apresentar modos como a existência dos vírus pode afetar a divulgação científica, tangenciando diálogos com a educação e o ensino de ciências e biologia.
Tiago Amaral Sales, Susana Oliveira Dias
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