Results 31 to 40 of about 1,983,859 (250)
Revealing the hidden diversity of Chlorella heliozoae-infecting giant viruses
npj VirusesA new level of viral complexity has emerged from the isolation of green algae-infecting chloroviruses from diverse aquatic environments around the world over the past few decades.
Lethícia R. Henriques +8 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Programa Nacional de Vigilância da Gripe: relatório da época 2012/2013 [PDF]
, 2013 Com o presente relatório, o Instituto Nacional de Saúde Doutor Ricardo Jorge, I.P., pretende sintetizar e divulgar os resultados obtidos pelo Programa Nacional de Vigilância da Gripe (PNVG) durante a época de 2012/2013, em Portugal.
Conde, Patrícia +4 more
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
BMC Infectious Diseases, 2017 Background In chronic hepatitis C, the fibrosis progression rates are extremely variable and can be influenced by factors associated with the host, virus and environment.
Mariana Cavalheiro Magri +5 more
doaj +1 more source
Representing and coding the knowledge embedded in texts of Health Science Web published articles [PDF]
, 2007 Despite the fact that electronic publishing is a common activity to scholars electronic journals are still based in the print model and do not take full advantage of the facilities offered by the Semantic Web environment.
Costa, Leonardo Cruz +5 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Programa Nacional de Vigilância da Gripe: relatório da época 2013/2014 [PDF]
, 2014 Na época de vigilância 2013/2014 a atividade gripal foi moderada com taxa de incidência máxima de 88,3 casos de SG por 100 000 habitantes na semana 4/2013.
Conde, Patrícia +4 more
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
DEVIR COM OS VÍRUS NO ANTROPOCENO
Revista da SBEnBIOBuscamos, neste artigo, apresentar modos como a existência dos vírus pode afetar a divulgação científica, tangenciando diálogos com a educação e o ensino de ciências e biologia.
Tiago Amaral Sales, Susana Oliveira Dias
doaj +1 more source