Results 41 to 50 of about 1,983,859 (250)

Állategészségügyi és közegészségügyi jelentőségű vírusok molekuláris diagnosztikája és filogenetikai analízise = Molecular diagnosis and phylogenetic analysis on viruses with veterinary- and human health importance [PDF]

open access: yes, 2008
A támogatási időszakban végzett kutatások során munkatársaimmal molekuláris biológiai módszerekre alapozott diagnosztikai eljárásokat dolgoztunk ki a nyugat-nílusi vírus, az Usutu vírus, a mézelő méh hat különböző vírusa, a Tahyna vírus, egy sertés ...
Bakonyi, Tamás
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Screening for Zika virus RNA in sera of suspected cases: a retrospective cross-sectional study

open access: yesVirology Journal, 2018
Background Zika virus (ZIKV) became a global human health concern owing to its rapid spread worldwide and its association with congenital and neurological disorders.
Lívia Sacchetto   +10 more
doaj   +1 more source

Ocorrência do vírus do mosaico severo (Cowpea severe mosaic virus - CPSMV) no feijão-caupi (Vigna unguiculata (L.) Walp.) em Rondônia. [PDF]

open access: yes, 2011
O objetivo deste trabalho foi relatar a ocorrência do vírus do mosaico severo, causada por cowpea severe mosaic vírus (CPSMV) em feijão caupi no Estado de Rondônia.bitstream/item/28308/1/cot353-virusdomosaicosevero ...
ANTUNES JÚNIOR, H.   +8 more
core  

Korszakváltás a krónikus C-vírus hepatitis terápiájában – új direkt ható antivirális szerek [PDF]

open access: yes, 2015
Absztrakt A krónikus C-vírus hepatitis kezelés nélkül 15–25 év alatt májzsugort, májelégtelenséget, májrákot okozhat.
Halász, Tünde   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

In-depth analysis of the replication cycle of Orpheovirus

open access: yesVirology Journal, 2019
Background After the isolation of Acanthamoeba polyphaga mimivirus (APMV), the study and search for new giant viruses has been intensified. Most giant viruses are associated with free-living amoebae of the genus Acanthamoeba; however other giant viruses ...
Fernanda Souza   +5 more
doaj   +1 more source

Vírus em macieira. [PDF]

open access: yes, 2019
Made available in DSpace on 2012-06-23T01:01:56Z (GMT). No. of bitstreams: 1 NICKELCultivarHFv2n13p312002.pdf: 825798 bytes, checksum: 063ef619a5bd29c8a33afbcffefd37b8 (MD5) Previous issue date: 2005-02 ...
NICKEL, O.
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Infecção viral da vinha nos Biscoitos (ilha Terceira) - Açores Grapevine virus infection at Biscoitos (Terceira island) - Azores

open access: yesRevista de Ciências Agrárias, 2009
A região dos Biscoitos na ilha Terceira, nos Açores, é mundialmente conhecida pela vinha em curraletas destinada à produção de Vinhos Licorosos de Qualidade Produzidos em Região Demarcada (VLQPRD).
Arícia Figueiredo   +2 more
doaj  

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