Results 61 to 70 of about 1,983,859 (250)

Investigation of Human IFITM3 Polymorphisms rs34481144A and rs12252C and Risk for Influenza A(H1N1)pdm09 Severity in a Brazilian Cohort

Frontiers in Cellular and Infection Microbiology, 2020
Influenza is a major public health problem that causes acute respiratory infection in humans. Identification of host factors influencing in disease outcome is critical for recognition of individuals with increased risk.
Jéssica S. C. Martins, Maria L. A. Oliveira, Cristiana C. Garcia, Marilda M. Siqueira, Aline R. Matos   +4 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Viroses da bananeira. [PDF]

, 2011
A cultura da bananeira pode ser infectada por diversas viroses, como o vírus do topo em leque da bananeira, o vírus das estrias da bananeira, o vírus do mosaico do pepino, o vírus do mosaico das brácteas da bananeira, o Banana mild mosaic virus, o Banana
MEISSNER FILHO, P. E.
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Sem vírus, mais vigor

Agropecuária Catarinense, 2017
Desde o início da década de 1990, quando o alho chinês desembarcou no Brasil, os produtores catarinenses vêm perdendo espaço no mercado nacional. A área plantada no País, na época, somava 18 mil hectares e Santa Catarina era o principal produtor, com 4,4
Cinthia Andruchak Freitas
doaj  

Presença do vírus da síndrome da mancha branca em crustáceos decápodes silvestres em lagoas costeiras no Sul do Brasil

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2012
A presença do vírus da síndrome da mancha branca (em inglês WSSV) nas principais espécies de camarões, siris e caranguejos de cinco lagoas que recebem o efluente de fazendas afetadas pela enfermidade foi detectada por nested PCR, e inclusões virais nos ...
S.W. Costa, A.P.M. Fraga, A.S. Zamparetti, M.R.F. Marques, E.R. Andreatta   +4 more
doaj   +1 more source

Identificação de genótipos de Manihot sp. com alelos de resistência ao vírus do Mosaico Africano. [PDF]

, 2012
O vírus do mosaico africano da mandioca (Cassava mosaic disease - CMD) é a virose mais importante da cultura, sendo encontrada na África, Índia, Malásia e Ásia.
FERREIRA, C. F., LEDO, C. A. da S., OLIVEIRA, E. J. de, OLIVEIRA, G. A. F., SILVEIRA, T. C. da, VIEIRA, L. de J.   +5 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Poszt-transzkripcionális géncsendesítés és szupresszió molekuláris mechanizmusának feltárása növényekben = Unraveling the mechanism of Post-transcriptional gene silencing and suppression in plants [PDF]

, 2008
Az RNS silencing, egy géninaktivációs mechanizmus, amely szinte az összes eukarióta szervezetben működik, és magába foglalja az állati RNS interferencia és a növényi poszt-ranszkripcionális géncsendesítés (PTGS) jelenségét.
Burgyán, József, Molnár, Attila, Szittya, György, Várallyay, Éva   +3 more
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source