Interplay of vacuolar transporters for coupling primary and secondary active transport
Secondary active transporters are driven by the proton motif force which is generated by primary active transporters such as the vacuolar proton pumps V-ATPase and V-PPase.
Michèle Siek +5 more
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PI(4)P directly interacts with the cytosolic domain of yeast Golgi vacuolar H+-ATPase (V-ATPase) a-isoform, Stv1, and the human Golgi a-subunit isoform. Lys-84 of Stv1 is essential for PI(4)P interaction, and localization of Stv1-containing V-ATPases in ...
Subhrajit Banerjee, P. Kane
semanticscholar +1 more source
Imaging and 3D reconstruction of membrane protein complexes by cryo-electron microscopy and single particle analysis [PDF]
Cryo-electron microscopy (cryo-EM) in combination with single particle image processing and volume reconstruction is a powerful technology to obtain medium-resolution structures of large protein complexes, which are extremely difficult to crystallize and ...
Gregorini, Marco
core +1 more source
V-ATPases and Their Implication in Oral Cancer
The control of intracellular and extracellular pH is extremely important for many biological functions and the condition of hypoxia is a frequent phenomenon during the development of oral squamous cell carcinoma (OSCC). The cellular acidosis appears to be controlled, mainly, by the vacuolar-type H+ ATPase (V-ATPase), which is clearly involved in ...
Oliveira Alves, Monica Ghislaine +4 more
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Yang‐ja Lee, Reed B. Wickner
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Validation of the Target Protein of Insecticidal Dihydroagarofuran Sesquiterpene Polyesters
A series of insecticidal dihydroagarofuran sesquiterpene polyesters were isolated from the root bark of Chinese bittersweet (Celastrus angulatus Max).
Lina Lu, Zhijun Qi, Qiuli Li, Wenjun Wu
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Bjørbæk, C., Foërsom, V. and Michelsen, O., The transmembrane topology of the a subunit from the ATPase in Escherichia coli analyzed by PhoA protein fusions (1990) FEBS Letters 260, 31‐34 [PDF]
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Summary In the past two decades, chloroplast genetic engineering has been advanced to achieve high‐level protein accumulation but not for down‐regulation of targeted genes.
Shuangxia Jin +4 more
semanticscholar +1 more source
Background: The V-ATPase proton pump controls acidification of intra and extra-cellular milieu in both physiological and pathological conditions. We previously showed that some V-ATPase subunits are enriched in glioma stem cells and in patients with poor
Irene Bertolini +13 more
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A V-ATPase DRIVES ACTIVE, ELECTROGENIC AND Na+-INDEPENDENT Cl−ABSORPTION ACROSS THE GILLS OF ERIOCHEIR SINENSIS [PDF]
Horst Onken, M. Putzenlechner
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