Results 161 to 170 of about 10,440,305 (287)

PfATG18 links V-ATPase assembly to endocytic membrane dynamics in malaria parasites. [PDF]

PLoS Pathog
Schmitz Y, Sengupta M, Schneider C, Ziesmann T, Hellmold F, Distler U, Reimer R, Matz JM.   +7 more
europepmc   +1 more source

Donor‐Cell Senescence Redirects PINK1‐Marked Mitochondrial Cargo From Mitophagy to Microvesicle Transfer Through SUMO3‐Stabilized HSPA9

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicle therapies have been developed for tissue repair, but how donor‐cell senescence reshapes vesicle‐mediated mitochondrial transfer remains unclear. Here, we show that senescent adipose‐derived stem cells (ADSCs) redirect damaged mitochondria into microvesicles (MVs), converting protective vesicles into pro‐degenerative ...
Zixuan Ou, Mingke Zhao, Zhiwei Ling, Lianqi Peng, Bide Tong, Huaizhen Liang, Hongchuan Wang, Di Wu, Yifan Du, Zhi Du, Shihao Zhang, Yuyuan Jia, Yifan Qian, Gan Xu, Liuliang He, Gang Li, Shun Zhang, Lei Tan, Kun Wang, Xiaobo Feng, Cao Yang, Zhiwei Liao   +21 more
wiley   +1 more source

Renoprotective effects of tubular glucagon receptor activation mediated by V-ATPase. [PDF]

Sci Adv
Qu H, Xu M, Du P, Zhang L, Wang W, Liu X, Zhu J, Tian C, He Q, Li J, Tao Y, Gong Z, Yang Q, Zheng Y, Zheng H.   +14 more
europepmc   +1 more source

Lithium‐Doped Hydroxyapatite Nanowires Rejuvenate Senescent Macrophages Via the Lysosome‐Dependent Ferroptosis Axis to Promote Aged Bone Regeneration

Advanced Science, EarlyView.
Li‐nHAP+GelMA promotes mandibular bone regeneration in aged mice by remodeling the senescent immune microenvironment. Local delivery of Li‐nHAP restores lysosomal homeostasis in senescent macrophages, reduces intracellular labile Fe2+ accumulation, ROS production, and lipid peroxidation, thereby suppressing macrophage ferroptosis and senescence ...
Baixi Chen, Ziduan Ding, Ruomei Li, Cheng Zhu, Zhiyu Zhu, Zitong Yang, Luyao Qu, Jin Hao, Lunguo Xia, Bing Fang, Lu Liu   +10 more
wiley   +1 more source

AP-3 and the V-ATPase modulate CTP synthase assembly through spatial association at the yeast vacuole. [PDF]

Mol Biol Cell
McCright M, Leih M, Nack A, Angers CG, Merz AJ, Odorizzi G.   +5 more
europepmc   +1 more source

Editorial: Structure and Function of F- and V-ATPases [PDF]

Frontiers in Physiology, 2019
Bernardi P., Lippe G.
openaire   +3 more sources

CaMKIIδ Phosphorylates AUP1 to Promote Pancreatic Tissue Repair and Acinar‐to‐Ductal Metaplasia Formation via Mediating PERK‐Dependent Unfolded Protein Responses

Advanced Science, EarlyView.
CaMKIIδ–AUP1 signaling maintains PERK‐dependent ER homeostasis during ADM‐mediated pancreatic repair. ABSTRACT Pancreatic repair after acute pancreatitis (AP) is essential for restoring tissue integrity, but the intrinsic mechanisms coordinating acinar plasticity and regeneration remain poorly understood.
Yonghao Chen, Ziying Han, Zihan Yang, Jie Wu, Kaixin Peng, Xiuli Zhang, Bintao Qiu, Jianqiang Wu, Xiaomin Hu, Dong Wu, Li Wen   +10 more
wiley   +1 more source

Granular Cell Dermatofibroma Demonstrates Loss-of-Function Mutations in V-ATPase Component Genes. [PDF]

J Cutan Pathol
Jiang X, Hu R, Choate KA, Panse G.
europepmc   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

Advanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler, Alejandra Vasquez Limeta, Ernesto Reyes Sanchez, Leah Carter, Francisco Altamirano   +4 more
wiley   +1 more source

S-palmitoylation of the v-ATPase subunit RNAseK is necessary for Zika virus infection. [PDF]

Virol J
Leiva S, Recordon-Pinson P, Fischer L, Andreola ML, Thinon E.   +4 more
europepmc   +1 more source