Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology
Objective Early phenotypic presentation of central afferent synapse dysfunction within patients with spinal muscular atrophy (SMA) represents a key target for therapeutic development; however, the underlying disease mechanisms remain unresolved. By further investigating motor neuron synapse and peri‐synaptic astrocyte process (PAP) defects in human SMA
Emily Welby +6 more
wiley +1 more source
Synthesis of Diphenyl Sulfonamide Derivatives as Potential Inhibitors of V-ATPase. [PDF]
Tian M +10 more
europepmc +1 more source
A single small molecule-based human embryo model reveals V-ATPase requirement in mammalian blastocyst cavitation. [PDF]
Alsolami S +20 more
europepmc +1 more source
Rab14 restricts pathogens by promoting V-ATPase lysosomal delivery to drive lysosomal acidification. [PDF]
Lei Z +18 more
europepmc +1 more source
Vacuolar ATPase regulates ureteric bud branching morphogenesis during kidney development. [PDF]
Yosypiv IV, Liu H, Nakhoul NL.
europepmc +1 more source
A self-sensing vacuole/lysosome: V-ATPase dysfunction activates selective autophagy. [PDF]
Huang Y, Klionsky DJ.
europepmc +1 more source
Correction: CLC3 regulates V-ATPase to enhance lysosomal degradation and cisplatin resistance in cervical cancer cells. [PDF]
Chen C +9 more
europepmc +1 more source
Correction: NCOA7 inhibits renal cancer progression by inducing autophagy and lipid metabolism through V-ATPase interaction. [PDF]
Wang J +7 more
europepmc +1 more source
Field samples from breeder duck farms with egg‐production decline were subjected to viral detection, genome sequencing, and virus isolation. Experimental infection demonstrated that duck orbivirus (DORV) causes a significant and persistent reduction in egg production in breeder ducks.
Bing Li +18 more
wiley +1 more source
Surface charge of LNP and V-ATPase activity of target cell synergize in functional delivery of nucleic acid <i>in vitro</i> and <i>in vivo</i>. [PDF]
Yang Z +8 more
europepmc +1 more source

