Results 211 to 220 of about 147,751 (260)

The ROGDI protein mutated in Kohlschutter-Tonz syndrome is a novel subunit of the Rabconnectin-3 complex implicated in V-ATPase assembly. [PDF]

J Biol Chem
Winkley SR, Kane PM.
europepmc   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

DNLA Delayed the Appearance of Learning and Memory Impairment of APP/PS1 Mice: Involvement of mTOR/TFEB/v-ATPase Signaling Pathway. [PDF]

CNS Neurosci Ther
Wu Y, Liu X, Luo G, Li Q, Guo B, Li L, Nie J.   +6 more
europepmc   +1 more source

The different roles of V-ATPase a subunits in phagocytosis/endocytosis and autophagy. [PDF]

Autophagy
Chen Q, Kou H, Demy DL, Liu W, Li J, Wen Z, Herbomel P, Huang Z, Zhang W, Xu J.   +9 more
europepmc   +1 more source

Big1 is a newly identified autophagy regulator that is critical for a fully functional V-ATPase. [PDF]

Mol Biol Cell
Lei Y, Yang Y, Zhang Z, Zhang R, Song X, Malek SN, Tang D, Klionsky DJ.   +7 more
europepmc   +1 more source

Reticulophagy mediated by the V-ATPase-ATG16L1-LC3C axis. [PDF]

Autophagy
Sun Y, Wang X.
europepmc   +1 more source

The V-ATPase as drug target

, 2018
Huss, M., Bender, Tobias, Grond, S., von Zezschwitz, Paultheo, Kunze, Brigitte, Sasse, Florenz, Menche, D., Wieczorek, H.   +7 more
openaire   +1 more source

The pH-sensitive translocation of V-ATPase in the small airway of cystic fibrosis pigs.

Am J Physiol Lung Cell Mol Physiol
Villacreses R, Thornell IM, Li X, Mather SE, Urbano J, Stoltz DA, Zabner J.   +6 more
europepmc   +1 more source

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Structure and Regulation of the V-ATPases

Journal of Bioenergetics and Biomembranes, 2005
The V-ATPases are ATP-dependent proton pumps present in both intracellular compartments and the plasma membrane. They function in such processes as membrane traffic, protein degradation, renal acidification, bone resorption and tumor metastasis. The V-ATPases are composed of a peripheral V(1) domain responsible for ATP hydrolysis and an integral V(0 ...
Takao, Inoue, Yanru, Wang, Kevin, Jefferies, Jie, Qi, Ayana, Hinton, Michael, Forgac   +5 more
openaire   +2 more sources

V-ATPases as Drug Targets

Journal of Bioenergetics and Biomembranes, 2005
V-ATPases are large, complex enzymes responsible for acidification of many internal compartments in eukaryotic cells. They also occur on plasma membranes of specialized cells, where they acidify the surrounding milieu. Numerous physiological processes depend on the activity of V-ATPases, and V-ATPases are implicated as a contributing factor in multiple
Emma Jean, Bowman, Barry J, Bowman
openaire   +2 more sources