Results 211 to 220 of about 10,440,305 (287)

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Overcoming lysosomal barrier via V-ATPase: an exosome-based co-delivery platform for combined chemo/RNAi therapy against breast cancer. [PDF]

J Nanobiotechnology
Liu K, Xiong T, Wang X, Wang T, Wang Y, Lei M, Shao L, Zhang L, Zhu Y.   +8 more
europepmc   +1 more source

Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

BMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu, Aohan Luan, Yujun Yang, Linlin Wang, Huilin Wang, Ning Wang, Guixin He, Yajie Yang, Rabiya Noor, Jawad Hussain, Longquan Shao   +10 more
wiley   +1 more source

V-ATPase and Lysosomal Energy Sensing in Periodontitis and Medicine-Related Osteonecrosis of the Jaw. [PDF]

Biomolecules
Yang X, Holliday LS.
europepmc   +1 more source

Critical mineral removal from mining‐impacted waters using microalgal biomass

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Rising demand for critical minerals has led to increased mining and mineral processing activities, resulting in the release of metal‐contaminated waters requiring treatment. Conventional treatment methods, such as lime neutralization, effectively precipitate metals; however, they are less effective at low metal concentrations and produce large
Sean Nickson, Corey A. Laamanen, John A. Scott   +2 more
wiley   +1 more source

Tributyltin induces conjugation of ATG8s to single membranes via the V-ATPase-ATG16L1 axis, leading to transcription factor EB activation in human cell lines. [PDF]

Arch Toxicol
Hatamiya S, Miyara M, Takahashi N, Oguro A, Kotake Y.   +4 more
europepmc   +1 more source

Microtubule Destabilizing Kinesins: A Historical Perspective and Thoughts for the Future

Cytoskeleton, EarlyView.
ABSTRACT The microtubule cytoskeleton plays critical roles in multiple cellular processes such as mitotic spindle assembly and chromosome segregation. Cells contain a number of microtubule‐associated proteins that regulate microtubule dynamics both temporally and spatially in cells. The microtubule depolymerizing kinesins include members of the Kinesin‐
Claire E. Walczak
wiley   +1 more source

SNX11 Deletion Inhibits Dabie bandavirus Infection by Interfering with the Assembly of V-ATPase. [PDF]

Pathogens
Liu T, Wang X, Fang Y, Zhang P, Sun Q, Li J, Wang S.   +6 more
europepmc   +1 more source

Captivated by Kinesin

Cytoskeleton, EarlyView.
ABSTRACT Few proteins have inspired as much curiosity as kinesin. Since its discovery 40 years ago, kinesin has become one of the best understood molecular machines in biology, yet it continues to reveal new questions about how cells organize and move their contents.
Ronald D. Vale
wiley   +1 more source

NCOA7 inhibits renal cancer progression by inducing autophagy and lipid metabolism through V-ATPase interaction. [PDF]

Cell Death Discov
Wang J, Luo H, He Q, Shao H, Cai X, Cao Y, Wang Y, Wang D.   +7 more
europepmc   +1 more source