Results 131 to 140 of about 443,126 (283)

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

open access: yesAdvanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han   +11 more
wiley   +1 more source

Overloading and Unpacking (OAK) - Multiome V1 v1

open access: yes
High-throughput single-cell sequencing is a powerful technique for investigating the cellular diversity of complex biological systems. Throughput, cost effectiveness, and experimental simplicity are crucial forefronts of technological advancement in profiling single cells.
Hayley Bennett, Bing Wu
openaire   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

open access: yesAdvanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann   +11 more
wiley   +1 more source

Separation of bimodal fMRI responses in mouse somatosensory areas into V1 and non-V1 contributions

open access: yesScientific Reports
Multisensory integration is necessary for the animal to survive in the real world. While conventional methods have been extensively used to investigate the multisensory integration process in various brain areas, its long-range interactions remain less ...
Thi Ngoc Anh Dinh   +2 more
doaj   +1 more source

Parallel pathways carrying direction-and orientation-selective retinal signals to layer 4 of the mouse visual cortex

open access: yesCell Reports
Summary: Parallel visual pathways from the retina to the primary visual cortex (V1) via the lateral geniculate nucleus are common to many mammalian species, including mice, carnivores, and primates.
Helen Wang   +5 more
doaj   +1 more source

CAMbank: Environmental Swabbing in Flight (v1) v1

open access: yes
This protocol details the standardized collection of environmental microbial samples from spacecraft interiors during flight, using sterile swabs and nucleic acid preservative to enable downstream microbial community analyses. During the SpaceX Inspiration4 mission, environmental swabs were collected from predetermined high-contact and representative ...
Eliah G Overbey   +4 more
openaire   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

open access: yesAdvanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung   +7 more
wiley   +1 more source

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy