Results 121 to 130 of about 443,126 (283)

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Fitness cost of tet(A) type I variant-mediated tigecycline resistance in Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance
Objective: The aim of the present study is to explore the impact of the tet(A) type I variant (tetA-v1) on its fitness effect in Klebsiella pneumoniae. Methods: Clinical K. pneumoniae strains were utilized as parental strains to generate strains carrying
Yuanyuan Li, Tianyu Wang, Yunbing Li, Chen Xu, Tianyi Wang, Lili Huang, Xiangkun Zeng, Guangfen Zhang, Chunli Li, Ning Dong   +9 more
doaj   +1 more source

Anti-Salmonella Activity Modulation of Mastoparan V1—A Wasp Venom Toxin—Using Protease Inhibitors, and Its Efficient Production via an Escherichia coli Secretion System

Toxins, 2017
A previous study highlighted that mastoparan V1 (MP-V1), a mastoparan from the venom of the social wasp Vespula vulgaris, is a potent antimicrobial peptide against Salmonella infection, which causes enteric diseases.
Yeon Jo Ha, Sam Woong Kim, Chae Won Lee, Chang-Hwan Bae, Joo-Hong Yeo, Il-Suk Kim, Sang Wan Gal, Jin Hur, Ho-Kyoung Jung, Min-Ju Kim, Woo Young Bang   +10 more
doaj   +1 more source

tim-peterson/R-graphing-statistics: v1

, 2020
<p>Creating v1 to prepare the ATRAID manuscript for its publication.</p ...
Tim Peterson
core   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

[RETRACTED] Diaetoxil v1

, 2022
[RETRACTED]Diaetoxil estime qu'il vous donnera le meilleur résultat sans nuire à votre corps. Vérifiez son prix, ses avantages et ses effets secondaires.
openaire   +1 more source

Tunable Negative Thermal Expansion in Fe/Cr‐Substituted Nd2Co17 Compounds via Magnetoelastic Coupling

Advanced Science, EarlyView.
This study achieves anisotropic thermal expansion tuning in Nd2(Co1‐xFex)17‐yCry compounds via a magnetoelastic strategy. Variable‐temperature synchrotron X‐ray diffraction reveals that increased Fe content induces switchable lattice responses. Compositional control reduces the volume expansion coefficient αV by 20% (x═0.7) and modulates TC (442–625 K),
Jiayuan Li, Chenfei Qv, Haoran Tu, Qinfen Gu, Wayne D. Hutchison, Stewart J. Campbell, Zhenxiang Cheng, Wenquan Wang, Jianli Wang   +8 more
wiley   +1 more source

Auditory cortex conveys non-topographic sound localization signals to visual cortex

Nature Communications
Spatiotemporally congruent sensory stimuli are fused into a unified percept. The auditory cortex (AC) sends projections to the primary visual cortex (V1), which could provide signals for binding spatially corresponding audio-visual stimuli.
Camille Mazo, Margarida Baeta, Leopoldo Petreanu   +2 more
doaj   +1 more source

Gamma Frequency and the Spatial Tuning of Primary Visual Cortex.

PLoS ONE, 2016
Visual stimulation produces oscillatory gamma responses in human primary visual cortex (V1) that also relate to visual perception. We have shown previously that peak gamma frequency positively correlates with central V1 cortical surface area.
Sarah Gregory, Marco Fusca, Geraint Rees, D Samuel Schwarzkopf, Gareth Barnes   +4 more
doaj   +1 more source

SEM-EDS Protocol V1 v1

This protocol outlines the methodology for conducting Scanning Electron Microscopy (SEM) and Energy-Dispersive X-ray Spectroscopy (EDS) analysis of laser-inscribed graphene (LIG) electrodes using a SU5000 microscope. The procedure details the preparation of LIG electrodes, their imaging under SEM, and subsequent elemental analysis via EDS. By combining
openaire   +1 more source