Results 21 to 30 of about 98,443 (105)

Association of Helicobacter pylori vacA genotypes and peptic ulcer in Iranian population: a systematic review and meta-analysis

BMC Gastroenterology, 2020
Helicobacter pylori is accounted as the most etiologic agent for digestive disorders, in particular, the most important of them i.e. peptic ulcer and gastric cancer.
M. Keikha, Mohammad Ali-Hassanzadeh, M. Karbalaei   +2 more
semanticscholar   +1 more source

A vaca louca

, 2016
Ensino Médio::BiologiaÁudio produzido a partir do acervo radiofônico da Rádio UFMG Educativa - Programa Papo de Vaca.
Mateus, Alfredo Luís
core   +2 more sources

Helicobacter pylori VacA-induced mitochondrial damage in the gastric pit cells of the antrum and therapeutic rescue.

Biomaterials
Exploring host cell specificity, pathogenicity, and molecular mechanisms of the vacuolating cytotoxin A (VacA), secreted by Helicobacter pylori (Hp) is crucial for developing novel treatment strategies.
Ye Seul Son, Y. H. Kwon, Moo-Seung Lee, Ohman Kwon, Yu-Jin Jeong, S. Mun, Sojeong Jeon, Ji Hye Park, Man-Hoon Han, Jae-Sung Bae, Keun Hur, Ah-Ra Jang, Jong-Hwan Park, Hyun-Soo Cho, Cho-Rok Jung, Choong-Min Ryu, M. J. Son, Doo-Sang Park, Mi-Young Son   +18 more
semanticscholar   +1 more source

VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection

Scientific Reports, 2019
Helicobacter pylori (H. pylori) is the causative agent of gastric cancer, making it the only bacterium to be recognized as a Class I carcinogen by the World Health Organization.
Majd Abdullah, Laura K. Greenfield, Dana M. Bronte-Tinkew, M. Capurro, D. Rizzuti, N. Jones   +5 more
semanticscholar   +1 more source

VacA genotypes and cagA‐EPIYA‐C motifs of Helicobacter pylori and gastric histopathological lesions

International Journal of Cancer, 2020
Helicobacter pylori infection induces inflammation of the gastric mucosa, which may progress to precancerous lesions and gastric cancer. The gastric histo‐pathological damages may be associated with some virulence genes of the bacterium, notably vacA and
Mounia El Khadir, S. Alaoui, D. Benajah, S. Ibrahimi, L. Chbani, M. El Abkari, B. Bennani   +6 more
semanticscholar   +1 more source

Mixed infection with cagA positive and cagA negative strains of Helicobacter pylori lowers disease burden in The Gambia. [PDF]

, 2011
BACKGROUND: The prevalence of Helicobacter pylori including strains with putatively virulent genotypes is high, whereas the H. pylori-associated disease burden is low, in Africa compared to developed countries.
Douglas E. Berg, Martin Antonio, Walton, Robert T., Mary Tapgun, Thomas Vivat, Thomas Julian E., Walton, R, Thomas, Vivat, Julian E Thomas, Tapgun, M., Corrah, T, Thomas, JE, Christian Bottomley, Tumani Corrah, Berg, D. E., Corrah, Tumani, Douglas E Berg, Adegbola, Richard A, Tapgun, M, Corrah Tumani, Bottomley, C, Robert Walton, Thomas, J., Corrah, T., Adegbola, R. A., Bottomley, C., Thomas, V., Antonio, M, Berg, Douglas E, Walton Robert, Richard A. Adegbola, Vivat Thomas, Secka, Ousman, Berg Douglas E., Richard A Adegbola, Bottomley, Christian, Ousman Secka, Tapgun, Mary, Secka, O, Tapgun Mary, Secka Ousman, Berg, DE, Julian E. Thomas, Secka, O., Thomas, Julian E, Walton, Robert, Antonio Martin, Thomas, V, Adegbola Richard A., Bottomley Christian, Adegbola, RA, Antonio, Martin   +51 more
core   +1 more source

Helicobacter pylori VacA Targets Myeloid Cells in the Gastric Lamina Propria To Promote Peripherally Induced Regulatory T-Cell Differentiation and Persistent Infection

mBio, 2019
Helicobacter pylori has coexisted with humans for at least 60.000 years and has evolved persistence strategies that allow it to evade host immunity and colonize its host for life. The VacA protein is expressed by all H. pylori strains and is required for
Aleksandra Altobelli, M. Bauer, Karelia Vélez, T. Cover, A. Müller   +4 more
semanticscholar   +1 more source

Helicobacter pylori vacA, cagA and iceA genotypes in dyspeptic patients from southwestern region, Saudi Arabia: distribution and association with clinical outcomes and histopathological changes

BMC Gastroenterology, 2019
BackgroundThe aim of this study was to identify the common H. pylori virulence genes among dyspeptic Southwestern Saudi patients and their association with clinical outcomes and histopathological findings to help practitioners and researchers in the ...
Mohammed A. Akeel, A. Shehata, A. Elhafey, E. Elmakki, Thanaa Aboshouk, H. Ageely, M. Mahfouz   +6 more
semanticscholar   +1 more source

Detection of Helicobacter pylori and its virulence genes (cagA, dupA, and vacA) among patients with gastroduodenal diseases in Chris Hani Baragwanath Academic Hospital, South Africa

BMC Gastroenterology, 2019
BackgroundThe global prevalence of H. pylori approaches 50%, with prevalence rates between 20 and 40% in developed countries and up to 90% in Africa and other developing nations of the world. Development of H.
A. Idowu, Asisipho Mzukwa, Ute Harrison, P. Palamides, R. Haas, M. Mbao, Razinah Mamdoo, J. Bolon, T. Jolaiya, Stella I. Smith, R. Ally, A. Clarke, H. Njom   +12 more
semanticscholar   +1 more source

Functional Properties of Helicobacter pylori VacA Toxin m1 and m2 Variants

Infection and Immunity, 2020
Helicobacter pylori colonizes the gastric mucosa and secretes a pore-forming toxin (VacA). Two main types of VacA, m1 and m2, can be distinguished by phylogenetic analysis.
Rhonda R. Caston, J. C. Sierra, N. J. Foegeding, Mandy D. Truelock, A. Campbell, A. Frick-Cheng, D. Bimczok, K. Wilson, M. S. McClain, T. Cover   +9 more
semanticscholar   +1 more source