Results 211 to 220 of about 3,236 (244)

Antigenic stability of H1N1 pandemic vaccines correlates with vaccine strain

Vaccine, 2011
In 2009 a novel H1N1 influenza virus emerged and spread rapidly. Soon after vaccine lots were released, however, the shelf life was revised downward due to an unexpected decrease in HA potency. In this study, we found differences in both stability and antigenic content of two monovalent H1N1/2009 vaccine preparations. These appear to have arisen due to
Aaron, Farnsworth, Terry D, Cyr, Changgui, Li, Junzhi, Wang, Xuguang, Li   +4 more
openaire   +2 more sources

BCG — different strains, different vaccines?

The Lancet Infectious Diseases, 2002
After nearly a century of use, BCG vaccines continue to generate controversy and confusion. Their ability to prevent tuberculosis in studies has been inconsistent. When they have been protective, no clear mechanism of action has been established. Furthermore, the existence of different BCG strains has been described since the 1940s.
openaire   +2 more sources

Defective interfering particles from poliovirus vaccine and vaccine reference strains

Virology, 1974
Abstract Defective interfering (DI) viral particles have been found to be associated with attenuated oral poliovirus vaccine and also with poliovirus vaccine reference strains. The DI particles replicate in low-passage human fibroblastic cells, the BSC-1 line of monkey kidney cells as well as in HeLa cells. DI particles of the attenuated polioviruses
L C, McLaren, J J, Holland
openaire   +2 more sources

Stable Recombinant Avirulent Salmonella Vaccine Strains

1989
All infectious disease agents have specific mechanisms to colonize , invade , and overcome the host. By use of gene cloning and genetic and biochemical techniques , it is possible to elucidate these mechanisms in biochemical terms as well as to understand the biology by which pathogens accomplish these feats .
R, Curtiss, S M, Kelly, P A, Gulig, K, Nakayama   +3 more
openaire   +2 more sources

Selection of influenza vaccine strains and developing pandemic vaccines

Vaccine, 2002
The WHO Influenza Surveillance Programme has recently celebrated 50 years of success. The programme provides representative influenza viruses for antigenic and genetic analysis and from this information, the WHO is able to make recommendations on vaccine composition.
openaire   +2 more sources

Orally administrable brucellosis vaccine: Brucella suis strain 2 vaccine

Vaccine, 1986
An orally administrable brucellosis vaccine, Brucella suis strain 2 vaccine was developed in China. The characteristics and merits of the vaccine are described. It is effective for oral vaccination of sheep, goats, cattle and pigs and has been widely used for prevention of animal brucellosis in China over the past 15 years. About 30-40 million doses of
openaire   +2 more sources

Mixed populations in influenza virus vaccine strains

Vaccine, 1994
Human influenza viruses used for vaccine production have previously been adapted to grow in eggs. During egg adaptation, variants are selected and we have observed that more than one variant may derive in a single egg resulting in a mixed population. We have now investigated the extent of heterogeneity, due to host cell selection, of virus strains used
J S, Robertson, P, Cook, C, Nicolson, R, Newman, J M, Wood   +4 more
openaire   +2 more sources

Mumps vaccine virus strains and aseptic meningitis

Vaccine, 2006
Mumps immunization can easily be included in national schedules, particularly if combined with measles or measles and rubella vaccines, but debate continues concerning the relative safety of various licensed mumps vaccine strains. The opportunities for control of mumps are also being affected by differences in the cost of the vaccines prepared with ...
Marie-Claude, Bonnet, Anil, Dutta, Clement, Weinberger, Stanley A, Plotkin   +3 more
openaire   +2 more sources

Vaccine escape of piliated Streptococcus pneumoniae strains

Vaccine, 2016
Type1-pilus proteins were suggested as targets of future protein-based vaccines. Here we studied the effect of pneumococcal-conjugate vaccine (PCV7) implementation on the prevalence of piliated strains in a unique study setting which controls for typical confounders; the Palestinian-Israeli Collaborative Research (PICR).Annual cross-sectional surveys ...
Gili, Regev-Yochay, Hanaa, Jaber, Ayob, Hamdan, Muhannad, Daana, Hanan, Nammouz, Amin, Thalji, Fuad, Jaar, Ziad, Abdeen, Carmit, Rubin, Amit, Huppert, Meir, Raz, Galia, Rahav   +11 more
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Cendehill strain of rubella vaccine: Clinical evaluation

The Journal of Pediatrics, 1969
Rubella vaccine, the Cendehill strain, was evaluated clinically and by measuring the hemagglutination-inhibition antibody response in the sera of both children and young women. In both groups of susceptible individuals, an antibody response occurred in over 99 per cent. The titer in children has remained fairly constant for at least 9 months.
J D, Farquhar, S A, Plotkin, R J, Schoengold   +2 more
openaire   +2 more sources