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, 2013 Since vaccination was documented by Edward Jenner in 1798, it has become the most successful means of preventing infectious diseases, saving millions of lives every year. However, application of vaccines is currently not limited to the prevention of infectious diseases.
Jiskoot, W. +2 more
openaire +4 more sources
Vaccines, Vaccination, and Vaccinology [PDF]
The Journal of Infectious Diseases, 2003 Although the demonstration in 1796 by Edward Jenner that vaccinia virus could protect against smallpox was epochal, he was following the path opened by the ancients who had used the smallpox virus itself in the practice of variolation. The work of Louis Pasteur on chicken cholera opened the way to vaccine development in the laboratory.
openaire +3 more sources
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source
npj VaccinesPersistent infection with high-risk human papillomavirus (HPV) is widely recognized as the primary cause of cervical and other malignant cancers. There are six licensed prophylactic vaccines available against HPV, but none of them shows any significant ...
Xueer Zhao +10 more
doaj +1 more source
Fractal dimension based geographical clustering of COVID-19 time series data
Scientific Reports, 2023 Understanding the local dynamics of COVID-19 transmission calls for an approach that characterizes the incidence curve in a small geographical unit. Given that incidence curves exhibit considerable day-to-day variation, the fractal structure of the time ...
Yessika Adelwin Natalia +5 more
doaj +1 more source
Promoting Healthy Ageing in South Africa Through Vaccination of the Elderly
Frontiers in Public Health, 2021 The World Health Organization estimates that globally, the proportion of people aged ≥60 years will more than double by the year 2050, with the majority of elderly people living in low- and middle-income countries such as South Africa.
Mncengeli Sibanda +7 more
doaj +1 more source
Analysis of COVID-19 in India using vaccine epidemic model incorporating vaccine effectiveness and herd immunity [PDF]
arXiv, 2022 COVID-19 will be a continuous threat to human population despite having a few vaccines at hand until we reach the endemic state through natural herd immunity and total immunization through universal vaccination. However, the vaccine acts as a practical tool for reducing the massive public health problem and the emerging economic consequences that the ...
arxiv
Asymmetric participation of defenders and critics of vaccines to debates on French-speaking Twitter [PDF]
Sci Rep 10, 6599 (2020).
https://doi.org/10.1038/s41598-020-62880-5, 2019 For more than a decade, doubt about vaccines has become an increasingly important global issue. Polarization of opinions on this matter, especially through social media, has been repeatedly observed, but details about the balance of forces are left unclear.
arxiv +1 more source
Nature Network Boston, 2022 In July 2022, the ongoing monkeypox (MPX) outbreak was declared a public health emergency of international concern. Modified vaccinia Ankara—Bavarian Nordic (MVA-BN, also known as Imvamune, JYNNEOS or Imvanex) is a third-generation smallpox vaccine that ...
Luca M. Zaeck +18 more
semanticscholar +1 more source
Impact of a mass vaccination campaign against a meningitis epidemic in a refugee camp. [PDF]
, 1996 Serogroup A meningococcus epidemics occurred in refugee populations in Zaire in August 1994. The paper analyses the public health impact of a mass vaccination campaign implemented in a large refugee camp.
Blok, L +5 more
core +2 more sources