Results 31 to 40 of about 4,303 (127)

Vaccine‐induced immune thrombotic thrombocytopenia presenting with normal platelet count

Research and Practice in Thrombosis and Haemostasis, 2021
Adenoviral‐vector based vaccines for coronavirus disease 2019 (COVID‐19) have been linked with a thrombotic syndrome, vaccine‐induced thrombotic thrombocytopenia (VITT).
David Page, Nancy Zhu, Daniel Sawler, Hao Wei Sun, Elona Turley, Menaka Pai, Cynthia Wu   +6 more
doaj   +1 more source

Thrombosis with thrombocytopenia after first dose of ChAdOx1 nCoV-19 vaccine: a case report

Neurologijos seminarai, 2021
More than 5 billion vaccine doses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been administered worldwide. In Lithuania, more than 1.72 million people have been vaccinated with at least one vaccine dose.
K. Kolodynskaja , S. Stankevičiūtė , A. Krikščionaitienė , N. Balčiūnienė   +3 more
doaj   +1 more source

Deterioration of vaccine‐induced immune thrombotic thrombocytopenia treated by heparin and platelet transfusion: Insight from functional cytometry and serotonin release assay

Research and Practice in Thrombosis and Haemostasis, 2021
We report a case of a 62‐year‐old man who developed cerebral venous sinus thrombosis with subarachnoid hemorrhage and concomitant thrombocytopenia, which occurred 13 days after ChAdOx1 nCov‐19 injection.
Alice Bérezné, David Bougon, Florence Blanc‐Jouvan, Nicolas Gendron, Cecile Janssen, Michel Muller, Sébastien Bertil, Florence Desvard, Isabelle Presot, Benjamin Terrier, Richard Chocron, Olivier Sanchez, Dominique Helley, David M. Smadja   +13 more
doaj   +1 more source

Diffuse prothrombotic syndrome after ChAdOx1 nCoV-19 vaccine administration: a case report

Journal of Medical Case Reports, 2021
Background Vaccine-induced immune thrombotic thrombocytopenia is emerging as one of the most relevant side effects of adenoviral-based vaccines against coronavirus disease 2019.
Nicole Ceschia, Valentina Scheggi, Anna Maria Gori, Angela Antonietta Rogolino, Francesca Cesari, Betti Giusti, Franco Cipollini, Niccolò Marchionni, Brunetto Alterini, Rossella Marcucci   +9 more
doaj   +1 more source

Pathogenic Mechanisms of Vaccine-Induced Immune Thrombotic Thrombocytopenia in People Receiving Anti-COVID-19 Adenoviral-Based Vaccines: A Proposal

Frontiers in Immunology, 2021
VITT is a rare, life-threatening syndrome characterized by thrombotic symptoms in combination with thrombocytopenia, which may occur in individuals receiving the first administration of adenoviral non replicating vectors (AVV) anti Covid19 vaccines ...
Bruno Azzarone, Irene Veneziani, Lorenzo Moretta, Enrico Maggi   +3 more
doaj   +1 more source

First diagnosis of thrombotic thrombocytopenic purpura after SARS-CoV-2 vaccine – case report

BMC Nephrology, 2021
Background We report a case of a 25-year-old male patient, who developed acquired thrombotic thrombocytopenic purpura (aTTP) after receiving a first dose of mRNA-based SARS-CoV-2 vaccine Spikevax (mRNA-1273, Moderna Biotech, USA). While this is the first
Bilgin Osmanodja, Adrian Schreiber, Eva Schrezenmeier, Evelyn Seelow   +3 more
doaj   +1 more source

Vaccine‐induced immune thrombotic thrombocytopenia (VITT) after SARS‐CoV‐2 vaccination: Two cases from Germany with unusual presentation

Clinical Case Reports, 2023
Vaccine‐induced immune thrombotic thrombocytopenia (VITT) is a rare clinical condition that has emerged during the mass immunization against SARS‐CoV‐2.
Rhea Edmonds, Linda Schönborn, Sunke Habben, Maria Paparoupa, Andreas Greinacher, Frank Schuppert   +5 more
doaj   +1 more source

Antibody-mediated procoagulant platelets in SARS-CoV-2-vaccination associated immune thrombotic thrombocytopenia

Haematologica, 2021
The COVID-19 pandemic has resulted in significant morbidity and mortality worldwide. To prevent severe infection, mass COVID-19 vaccination campaigns with several vaccine types are currently underway. We report pathological and immunological findings in
Karina Althaus, Peter Möller, Günalp Uzun, Anurag Singh, Annika Beck, Martin Bettag, Hans Bösmüller, Martina Guthoff, Franziska Dorn, Gabor C. Petzold, Hans Henkes, Nils Heyne, Hassan Jumaa, Kornelia Kreiser, Caroline Limpach, Beate Luz, Matthias Maschke, Janis A. Müller, Jan Münch, Simon Nagel, Bernd Pötzsch, Jens Müller, Christoph Schlegel, Andreas Viardot, Hansjörg Bäzner, Marc Wolf, Lisann Pelzl, Verena Warm, Winfried A. Willinek, Jochen Steiner, Nicole Schneiderhan-Marra, Dominik Vollherbst, Ulrich J. Sachs, Falko Fend, Tamam Bakchoul   +34 more
doaj   +1 more source

Vaccine‐induced prothrombotic immune thrombocytopenia without thrombosis may not require immune modulatory therapy: A case report

Research and Practice in Thrombosis and Haemostasis, 2022
Background Vaccine‐induced immune thrombotic thrombocytopenia (VITT) is a rare complication of the ChAdOx1 nCoV‐19 and Ad26.COV2.S COVID‐19 vaccines. It presents most commonly with severe thrombocytopenia and thrombotic complications with extremely high ...
Chieh Min Benjamin Lai, Agnes Y.Y. Lee, Stephen B.I. Parkin   +2 more
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source