Results 31 to 40 of about 32,135 (260)

Progress and Challenges in Measles and Rubella Elimination in the WHO European Region

Vaccines
The elimination of both measles and rubella remains a priority for all 53 Member States of the World Health Organization (WHO) European Region. To provide an update on the epidemiological status of measles and rubella in the Region, we reviewed ...
Mark Muscat, Myriam Ben Mamou, Catharina Reynen-de Kat, Dragan Jankovic, José Hagan, Simarjit Singh, Siddhartha Sankar Datta   +6 more
doaj   +1 more source

Genomic characterization of Haemophilus influenzae: a focus on the capsule locus

BMC Genomics, 2019
Background Haemophilus influenzae (Hi) can cause invasive diseases such as meningitis, pneumonia, or sepsis. Typeable Hi includes six serotypes (a through f), each expressing a unique capsular polysaccharide.
Caelin C. Potts, Nadav Topaz, Lorraine D. Rodriguez-Rivera, Fang Hu, How-Yi Chang, Melissa J. Whaley, Susanna Schmink, Adam C. Retchless, Alexander Chen, Edward Ramos, Gregory H. Doho, Xin Wang   +11 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

The impact of multiplex panel testing on ascertainment of pertussis-attributable, non-infant deaths: national surveillance from England

Journal of Clinical Microbiology
Understanding the burden of pertussis and pertussis-related mortality is important in enabling a better understanding of population vulnerability and supporting vaccination program planning.
Catherine Sandford Alber, Emer Cullen, Sonia Ribeiro, David J. Litt, Gayatri Amirthalingam, Helen Campbell, Sharif A. Ismail   +6 more
doaj   +1 more source

BMScan: using whole genome similarity to rapidly and accurately identify bacterial meningitis causing species

BMC Infectious Diseases, 2018
Background Bacterial meningitis is a life-threatening infection that remains a public health concern. Bacterial meningitis is commonly caused by the following species: Neisseria meningitidis, Streptococcus pneumoniae, Listeria monocytogenes, Haemophilus ...
Nadav Topaz, Dave Boxrud, Adam C. Retchless, Megan Nichols, How-Yi Chang, Fang Hu, Xin Wang   +6 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Comparison of traditional culture and molecular qPCR for detection of simultaneous carriage of multiple pneumococcal serotypes in African children

Scientific Reports, 2017
S. pneumoniae is a common colonizer of the human nasopharynx in high income and low-middle income countries. Due to limitations of standard culture methods, the prevalence of concurrent colonization with multiple serotypes is unclear.
Courtney P. Olwagen, Peter V. Adrian, Shabir A. Madhi   +2 more
doaj   +1 more source

Molecular characterization of invasive meningococcal isolates in Burkina Faso as the relative importance of serogroups X and W increases, 2008–2012

BMC Infectious Diseases, 2018
Background Neisseria meningitidis serogroup A disease in Burkina Faso has greatly decreased following introduction of a meningococcal A conjugate vaccine in 2010, yet other serogroups continue to pose a risk of life-threatening disease. Capsule switching
Adam C. Retchless, Malika Congo-Ouédraogo, Dinanibè Kambiré, Jeni Vuong, Alex Chen, Fang Hu, Absetou Ky Ba, Abdoul-Salam Ouédraogo, Soumeya Hema-Ouangraoua, Jaymin C. Patel, Rasmata Ouédraogo Traoré, Lassana Sangaré, Xin Wang   +12 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Assessing the risk of Guillain-Barré syndrome in older adults after bivalent RSV pre-F vaccination in England

Nature Communications
An elevated risk of Guillain-Barré syndrome following respiratory syncytial virus vaccination in older adults was reported from the United States in the first year of their programme. This national study assesses the risk of Guillain-Barré syndrome (GBS)
Julia Stowe, Conall H. Watson, Mary E. Ramsay, Nick J. Andrews   +3 more
doaj   +1 more source