Results 31 to 40 of about 857,892 (246)

Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine

New England Journal of Medicine, 2021
Background Efficacious vaccines are urgently needed to contain the ongoing coronavirus disease 2019 (Covid-19) pandemic of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
J. Sadoff, Mathieu le Gars, Georgi Shukarev, Dirk Heerwegh, C. Truyers, A. M. de Groot, Jeroen N. Stoop, Sarah M. Tete, W. Van Damme, I. Leroux-Roels, Pieter-Jan Berghmans, M. Kimmel, P. van Damme, J. D. de Hoon, William Smith, K. Stephenson, S. D. De Rosa, Kristen W. Cohen, M. McElrath, E. Cormier, Gert Scheper, D. Barouch, J. Hendriks, F. Struyf, M. Douoguih, J. van Hoof, H. Schuitemaker   +26 more
semanticscholar   +1 more source

Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial

Science, 2021
Description Antibody levels predict vaccine efficacy Symptomatic COVID-19 infection can be prevented by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.
P. Gilbert, D. Montefiori, A. McDermott, Y. Fong, D. Benkeser, Wei-zhi Deng, Honghong Zhou, Christopher R. Houchens, Karen Martins, L. Jayashankar, F. Castellino, B. Flach, Bob C. Lin, S. O'connell, C. McDanal, Amanda Eaton, M. Sarzotti-Kelsoe, Yiwen Lu, Chenchen Yu, Bhavesh Borate, Lars van der Laan, N. Hejazi, C. Huynh, Jacqueline Miller, Hana M. El Sahly, L. Baden, Mira Baron, Luis I. De La Cruz, C. Gay, Spyros A. Kalams, Colleen F. Kelley, M. Andrasik, J. Kublin, L. Corey, K. Neuzil, Lindsay N. Carpp, R. Pajon, D. Follmann, R. Donis, R. Koup   +39 more
semanticscholar   +1 more source

Emerging concepts in the science of vaccine adjuvants

Nature reviews. Drug discovery, 2021
Adjuvants are vaccine components that enhance the magnitude, breadth and durability of the immune response. Following its introduction in the 1920s, alum remained the only adjuvant licensed for human use for the next 70 years.
B. Pulendran, P. S. Arunachalam, D. O’hagan   +2 more
semanticscholar   +1 more source

Development of an inactivated vaccine candidate for SARS-CoV-2

Science, 2020
Vaccine candidate tested in monkeys Global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an urgent race to develop a vaccine. Gao et al.
Q. Gao, L. Bao, H. Mao, Lin Wang, K. Xu, Minnan Yang, Yajing Li, Ling Zhu, Nan Wang, Zhe Lv, Hong Gao, Xiaoqin Ge, B. Kan, Yalin Hu, Jiangning Liu, Fang Cai, D. Jiang, Yanhui Yin, C. Qin, Jing Li, X. Gong, X. Lou, W. Shi, Dongdong Wu, Hengming Zhang, Lang Zhu, Wei Deng, Yurong Li, Jinxing Lu, Changgui Li, Xiangxi Wang, W. Yin, Yanjun Zhang, Chuan Qin   +33 more
semanticscholar   +1 more source

Protection of BNT162b2 Vaccine Booster against Covid-19 in Israel

New England Journal of Medicine, 2021
Background On July 30, 2021, the administration of a third (booster) dose of the BNT162b2 messenger RNA vaccine (Pfizer–BioNTech) was approved in Israel for persons who were 60 years of age or older and who had received a second dose of vaccine at least ...
Y. Bar-On, Y. Goldberg, Michael I. Mandel, O. Bodenheimer, L. Freedman, N. Kalkstein, B. Mizrahi, S. alroy-Preis, N. Ash, R. Milo, A. Huppert   +10 more
semanticscholar   +1 more source

Vaccine and Vaccination: On Field Research

Vaccines, 2022
Historically, vaccinations have enabled the eradication, elimination, and control of many debilitating diseases [...]
Francesca Gallè, Christian Napoli
openaire   +3 more sources

SARS-CoV-2 mRNA Vaccine Design Enabled by Prototype Pathogen Preparedness

Nature, 2020
A vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is needed to control the coronavirus disease 2019 (COVID-19) global pandemic.
Kizzmekia S. Corbett, D. Edwards, S. Leist, O. Abiona, Seyhan Boyoglu-Barnum, Rebecca A. Gillespie, Sunny Himansu, A. Schäfer, Cynthia T Ziwawo, Anthony T. DiPiazza, K. Dinnon, Sayda M. Elbashir, C. Shaw, Angela Woods, Ethan J. Fritch, David R. Martinez, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Geoffrey B. Hutchinson, Kai Wu, C. Henry, Kapil Bahl, Dario Garcia-Dominguez, LingZhi Ma, Isabella Renzi, W. Kong, S. Schmidt, Lingshu Wang, Yi Zhang, Emily Phung, Lauren A. Chang, Rebecca J. Loomis, N. Altaras, Elisabeth Narayanan, Mihir Metkar, Vladimir Presnyak, Cuiping Liu, M. Louder, W. Shi, K. Leung, E. Yang, A. West, K. Gully, Laura J. Stevens, Nianshuang Wang, D. Wrapp, N. Doria-Rose, Guillaume B. E. Stewart-Jones, H. Bennett, Gabriela Alvarado, M. Nason, T. Ruckwardt, J. McLellan, M. Denison, J. Chappell, Ian N. Moore, Kaitlyn M. Morabito, J. Mascola, R. Baric, A. Carfi, B. Graham   +61 more
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Vaccine hesitancy: Beliefs and barriers associated with COVID‐19 vaccination among Egyptian medical students

Journal of Medical Virology, 2021
Vaccine hesitancy poses serious challenges for achieving coverage for population immunity. It is necessary to achieve high COVID‐19 vaccination acceptance rates and medical students’ coverage as future health care providers.
Shimaa M. Saied, E. Saied, I. Kabbash, Sanaa A Abdo   +3 more
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Overview of vaccines and vaccination [PDF]

Molecular Biotechnology, 2005
Of the 80-plus known infectious agents pathogenic for humans, there are now more than 30 vaccines against 26 mainly viral and bacterial infections and these greatly minimize subsequent disease and prevent death after exposure to those agents. This article describes the nature of the vaccines, from live attenuated agents to subunits, their efficacy and ...
openaire   +4 more sources

COVID-19 vaccine acceptance among pregnant women and mothers of young children: results of a survey in 16 countries

European Journal of Epidemiology, 2021
With the development of multiple effective vaccines, reducing the global morbidity and mortality of COVID-19 will depend on the distribution and acceptance of COVID-19 vaccination.
Malia Skjefte, Michelle Ngirbabul, Oluwasefunmi Akeju, Daniel J Escudero, S. Hernández-Díaz, D. Wyszynski, J. Wu   +6 more
semanticscholar   +1 more source