Results 41 to 50 of about 2,206,632 (403)

O-Acetylation is essential for functional antibody generation against Staphylococcus aureus capsular polysaccharide

Human Vaccines & Immunotherapeutics, 2018
Staphylococcus aureus produces an antiphagocytic polysaccharide capsule to evade neutrophil-mediated killing. Many vaccines against encapsulated bacterial pathogens require generation of functional anti-capsular antibodies to mediate protection against ...
Ingrid L. Scully, Viliam Pavliak, Yekaterina Timofeyeva, Yongdong Liu, Christine Singer, Annaliesa S. Anderson   +5 more
doaj   +1 more source

Immunotherapeutic Potential of CpG Oligonucleotides in Chickens

The Journal of Poultry Science, 2009
Synthetic oligodeoxynucleotides (ODN) containing CpG motifs activate innate and adaptive immune responses in numerous vertebrate species. The protective effects of CpG ODN against viral, bacterial and protozoal pathogens have been well documented in ...
Arshud Dar, Brenda Allan, Susantha Gomis, Andrew Potter, George Mutwiri   +4 more
doaj   +1 more source

پایداری و چرخش ارگانی ویروس تیپ o بیماری تب برفکی در خوکچه هندی [PDF]

Archives of Razi Institute, 2010
از آنجایی که خوکچه هندی به عنوان بهترین حیوان آزمایشگاهی حساس به ویروس بیماری تب برفکی مطرح شده است، مقدار یک میلی لیتر از ویروس تب برفکی تیپ O با غلظت TCID50 106-5/106به ناحیه کف پای 10 سر خوکچه هندی (سمت راست) به روش داخل پوستی تزریق شد.
محمد اسلام پناه, همایون مهروانی, محمدحسن حبل الورید, ح. ایزدی, م. ستوده, ف. جیرانی, ف. طالب لو   +6 more
doaj   +1 more source

Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]

, 2016
Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana, Chablani, Lipika, D\u27Souza, Martin J, Tawde, Suprita A   +3 more
core   +2 more sources

COVID-19 vaccine acceptance among pregnant women and mothers of young children: results of a survey in 16 countries

European Journal of Epidemiology, 2021
With the development of multiple effective vaccines, reducing the global morbidity and mortality of COVID-19 will depend on the distribution and acceptance of COVID-19 vaccination.
Malia Skjefte, Michelle Ngirbabul, Oluwasefunmi Akeju, Daniel J Escudero, S. Hernández-Díaz, D. Wyszynski, J. Wu   +6 more
semanticscholar   +1 more source

Challenges and opportunities in setting up a phase III vaccine clinical trial in resource limited settings: Experience from Nepal

Human Vaccines & Immunotherapeutics, 2021
Clinical trials are complicated, time-consuming and costly. From the initial screening, informed consent and recruitment of the participants’ to study completion, the sponsor must undertake a wide array of complex and closely monitored operations ...
Tarun Saluja, Bishnu Rath Giri, Shipra Chaudhary, Dipesh Tamrakar, Piush Kanodia, Sonali Palkar, Sridhar Vemula, Suchada Chinaworapong, Bomi Kim, Birendra Prasad Gupta, Sue Kyoung Jo, Sanet Aspinall, Ganesh Kumar Rai, Duncan Steele, Jerome H. Kim, T. Anh Wartel, Sushant Sahastrabuddhe   +16 more
doaj   +1 more source

Safety and immunogenicity of a reformulated Vietnamese bivalent killed, whole-cell, oral cholera vaccine in adults.

, 2007
Vietnam currently produces an orally administered, bivalent (O1 and O139) killed whole-cell vaccine and is the only country in the world with endemic cholera to use an oral cholera vaccine in public health practice.
Anh, Dang Duc, Attridge, Stephen, Canh, Do Gia, Carbis, Rodney, Clemens, John, Deen, Jacqueline, Han, Seung Hyun, Holmgren, Jan, Long, Phan Thi, Lopez, Anna Lena, Shin, Seong Hye, Son, Nguyen Hong, Thiem, Vu Dinh, von Seidlein, Lorenz   +13 more
core   +1 more source

Infection-acquired versus vaccine-acquired immunity in an SIRWS model [PDF]

, 2017
Despite high vaccine coverage, pertussis has re-emerged as a public health concern in many countries. One hypothesis posed for re-emergence is the waning of immunity.
Campbell, Patricia T, Frascoli, Federico, Hughes, Barry D, Leung, Tiffany, McCaw, James M   +4 more
core   +2 more sources

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

New England Journal of Medicine, 2020
Background Testing of vaccine candidates to prevent infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an older population is important, since increased incidences of illness and death from coronavirus disease 2019 (Covid-19 ...
E. Anderson, N. Rouphael, A. Widge, L. Jackson, P. Roberts, M. Makhene, J. Chappell, M. Denison, Laura J. Stevens, A. Pruijssers, A. McDermott, B. Flach, Bob C. Lin, N. Doria-Rose, S. O'Dell, S. Schmidt, Kizzmekia S. Corbett, P. Swanson, M. Padilla, K. Neuzil, H. Bennett, B. Leav, M. Makowski, J. Albert, Kaitlyn A. Cross, V. Edara, K. Floyd, M. Suthar, David R. Martinez, R. Baric, Wendy L. Buchanan, C. Luke, Varun K. Phadke, C. Rostad, J. Ledgerwood, B. Graham, J. Beigel   +36 more
semanticscholar   +1 more source

Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine

New England Journal of Medicine, 2021
BACKGROUND: Early clinical data from studies of the NVX-CoV2373 vaccine (Novavax), a recombinant nanoparticle vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that contains the full-length spike glycoprotein of the prototype ...
P. Heath, E. Galiza, D. Baxter, M. Boffito, D. Browne, Fiona Burns, D. Chadwick, R. Clark, C. Cosgrove, J. Galloway, A. Goodman, Amardeep Heer, A. Higham, Shalini Iyengar, A. Jamal, Christopher Jeanes, P. Kalra, Christina Kyriakidou, D. McAuley, Agnieszka Meyrick, A. Minassian, J. Minton, P. Moore, Imrozia Munsoor, Helen Nicholls, O. Osanlou, J. Packham, Carol H. Pretswell, Alberto San Francisco Ramos, D. Saralaya, R. Sheridan, Richard Smith, R. Soiza, P. Swift, E. Thomson, J. Turner, M. E. Viljoen, G. Albert, I. Cho, F. Dubovsky, G. Glenn, J. Rivers, A. Robertson, Kathy Smith, S. Toback   +44 more
semanticscholar   +1 more source