Results 131 to 140 of about 86,997 (265)

Biomimetic mineralization‐inspired formulation‐adjuvant integrated circRNA nanovaccine against COVID‐19

Interdisciplinary Medicine, EarlyView.
Inspired by the role of Mg2+ in stabilizing RNA secondary structures, we developed a one‐pot biomimetic mineralization method for synthesizing a circular RNA‐based nanovaccine (circRNA@FAiNVac) that integrates formulation and adjuvant functions. This nanovaccine exhibits potent immunostimulatory activation enabling multimodal immune responses and ...
Liangru Lin, Yingying Ren, Jing Li, Panxing Ren, Xinran Wang, Yixin Ding, Linsu Liu, Cong Liu, Zhou Li, Yan Liu, Dan Luo   +10 more
wiley   +1 more source

Comprehensive immunoprofiling and systematic adjuvant comparisons for identifying suitable vaccine: Adjuvant pairings. [PDF]

Hum Vaccin Immunother, 2023
Vázquez-Maldonado N, Kelly HR, Leitner WW.   +2 more
europepmc   +1 more source

Artificial cell: An emerging bioactive material with advanced applications in cancer theranostics

Interdisciplinary Medicine, EarlyView.
Artificial cells are emerging as attractive biomimetic bioactive materials that recapitulate key structures and functions of natural cells. This review systematically summarizes their major types, versatile fabrication strategies, tuneable properties and programmable biomimetic behaviours, highlights their cutting‐edge integrated applications in cancer
Daikun Wu, Shuo Yang, Hongjing Dou
wiley   +1 more source

Application of a small molecule calcium influx inducer as a vaccine adjuvant: enhancing Th2-biased immune responses. [PDF]

Front Immunol
Yokoyama Y, Sako Y, Yao S, Gil F, Cozza R, Jin J, Mclaughlin I, Anguiano Quiroz P, Brown T, Shukla NM, Chan M, Corr M, Carson DA, Hayashi T.   +13 more
europepmc   +1 more source

Unveiling the roles of extracellular vesicles in hematologic malignancies: Pathogenesis, diagnostic tools, and clinical translation

Interdisciplinary Medicine, EarlyView.
Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen, Zhiyuan Wu, Feng Zhang, Yuan Meng, Hongyan Liao, Tony Y. Hu   +5 more
wiley   +1 more source

Advances in vaccine adjuvant development and future perspectives. [PDF]

Drug Deliv
Sinani G, Şenel S.
europepmc   +1 more source

A novel defined TLR3 agonist as an effective vaccine adjuvant. [PDF]

Front Immunol, 2023
Ko KH, Cha SB, Lee SH, Bae HS, Ham CS, Lee MG, Kim DH, Han SH.   +7 more
europepmc   +1 more source

The Role of Artificial Intelligence in Modern Allergology: A Review of Applications in Diagnosis, Prediction, and Management

JEADV Clinical Practice, EarlyView.
ABSTRACT Artificial Intelligence is rapidly transforming allergology by enhancing diagnosis, risk prediction, automation, patient communication, education, and therapy development. Machine learning approaches, including convolutional neural networks, recurrent architectures, and transformer‐based models, enable analysis of complex datasets from ...
Sebastian Seurig, Stephan Traidl, Sonja Mathes   +2 more
wiley   +1 more source

Evaluation of Polymyxin B as a Novel Vaccine Adjuvant and Its Immunological Comparison with FDA-Approved Adjuvants. [PDF]

Vaccines (Basel)
Gulani M, Harsoda Y, Arte T, D'Souza MJ, Bagwe P, Adediran E, D'Souza N, Pasupuleti D.   +7 more
europepmc   +1 more source

Particulate Cell Wall Materials of Lactobacillus acidophilus as Vaccine Adjuvant. [PDF]

Vet Sci, 2022
Lin SC, Chang PC, Lin CH, Liang HJ, Huang CH.   +4 more
europepmc   +1 more source