A TLR7 Agonist Conjugated to a Nanofibrous Peptide Hydrogel as a Potent Vaccine Adjuvant. [PDF]
Euliano EM +9 more
europepmc +1 more source
Water-Soluble and Freezable Aluminum Salt Vaccine Adjuvant. [PDF]
Abucayon EG +6 more
europepmc +1 more source
Levamisole, as a viral vaccine adjuvant, induces robust host defense through the modulation of innate and adaptive immune responses. [PDF]
Kim GS +10 more
europepmc +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Picrasidine S Induces cGAS-Mediated Cellular Immune Response as a Novel Vaccine Adjuvant. [PDF]
Ding X +8 more
europepmc +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Development of a New Vaccine Adjuvant System Based on the Combination of the Synthetic TLR4 Agonist FP20 and a Synthetic QS-21 Variant. [PDF]
Shaik MM +10 more
europepmc +1 more source
From Cold to Hot: Nanozyme‐Based Strategies for Reprogramming the Tumour Immunoenvironment
Nanozymes, with multi‐enzyme catalytic activities, reprogram the immunosuppressive tumour microenvironment by inducing immunogenic cell death, relieving hypoxia, and depleting antioxidants, effectively converting immunologically “cold” tumours into “hot” ones to boost cancer immunotherapy efficacy.
Yue Wang +9 more
wiley +1 more source

