Results 151 to 160 of about 435,241 (348)

An Update on Human Papilloma Virus Vaccines: History, Types, Protection, and Efficacy [PDF]

open access: gold, 2022
Zahra Yousefi   +7 more
openalex   +1 more source

Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao   +10 more
wiley   +1 more source

Efficacy, Safety, and Public Attitude toward COVID-19 Vaccines: A Systematic Review

open access: hybrid, 2023
Blessing Osagumwendia Josiah   +4 more
openalex   +1 more source

Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation

open access: yesAdvanced Science, EarlyView.
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy   +16 more
wiley   +1 more source

Efficacy of tetravalent coryza vaccine against the challenge of Avibacterium paragallinarum serovars A and B isolates from Indonesia in chickens [PDF]

open access: gold, 2019
Agnesia Endang Tri Hastuti Wahyuni   +3 more
openalex   +1 more source

Vaccine, Booster and Natural Antibody Binding to SARS-CoV-2 Omicron (BA.1) Spike Protein and Vaccine Efficacy [PDF]

open access: green, 2022
Philip H. James‐Pemberton   +8 more
openalex   +1 more source

Antagonistic Ubiquitin Switching by USP7 and RNF40 Orchestrates KDM6A Homeostasis to License Coronavirus Susceptibility

open access: yesAdvanced Science, EarlyView.
We identify an antagonistic ubiquitin circuit that controls cellular permissiveness to multiple coronaviruses. The deubiquitinase USP7 stabilizes the epigenetic regulator KDM6A to upregulate viral receptors, while the E3 ligase RNF40 degrades KDM6A by catalyzing K6/K11‐ubiquitin chains of KDM6A for autophagic degradation.
Meng‐Zhuo Huang   +9 more
wiley   +1 more source

A Dynamic Model of Information-Vaccination-Disease That Accounts for Emerging Viral Variants: Model Development and a Case Study for COVID-19 in Iceland

open access: yesDiscrete Dynamics in Nature and Society
Pathogens mutate as diseases spread, and variants that become epidemic or pandemic strains have higher transmission rates and a greater capacity to escape vaccine protection.
Laijun Zhao   +4 more
doaj   +1 more source

Booster immunization with Ad26.COV2.S or Omicron adapted vaccine enhanced immune responses and efficacy against SARS-CoV-2 Omicron in non-human primates [PDF]

open access: green, 2022
Laura Solforosi   +24 more
openalex   +1 more source

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