Results 11 to 20 of about 2,076,500 (256)
Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS, S/AS01 malaria vaccine in African children. [PDF]
, 2011 BACKGROUND\ud
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There has been much debate about the appropriate statistical methodology for the evaluation of malaria field studies and the challenges in interpreting data arising from these trials.\ud
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METHODS\ud
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The present paper describes ...Amanda Leach, Bejon, P, Williamson John, Mohamed, Ali, Mohamed, A, Lievens, M, Mmbando Bruno, Lievens Marc, Williamson, John, Marc Lievens, John J Aponte, Ali Mohamed, Leach, Amanda, Bruno Mmbando, Aponte John J, Mmbando, Bruno, Philip Bejon, Bejon, Philip, Mmbando, B, Aponte, John J, Bejon Philip, Aponte, JJ, Lievens, Marc, Leach Amanda, Williamson, J, Leach, A, Mohamed Ali, John Williamson +27 morecore +1 more sourceFirst results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children. [PDF]
, 2011 BACKGROUND\ud
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An ongoing phase 3 study of the efficacy, safety, and immunogenicity of candidate malaria vaccine RTS,S/AS01 is being conducted in seven African countries.\ud
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METHODS\ud
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From March 2009 through January 2011, we enrolled 15,460 ...Machera, Francisca, Abdulla, Salim, Sillman, Marla, Maingi, Charity, Aide, Pedro, Hamad, AS, Sambian, D, Kremsner, Peter Gottfried, Mordmüller, B, Conzelmann, Cornelia, Maingi, C, Sylverken, J, Adjei, George, Sandrine, Y, Abdul, Omari, Owusu-Ofori, R, Drakeley, C, Ansong, D, Leach, Amanda, Urassa, AM, Radford, A, Kayan, K, Methogo, Barbara Gaelle Nfono Ondo, Carter, T, Bejon, Philip, Gondi, Stacey, Chome, Nelecy, Akoo, P, Doucka, Yannick, Aponte, John J, Guerra, Yolanda, Aponte, JJ, Valea, I, Chandramohan, Daniel, null null, Alonso, P, Jones, David, Liheluka, Edwin, Sillman, M, Loucq, Christian, Malabeja, A, Omoto, Jackton, Agnandji, ST, Nyakuipa, Dalitso, Quelhas, D, Flamen, Arnaud, Jongert, Erik, Ahmed, S, Otieno, Walter, Bassat, Quique, Slutsker, L, Mordmüller, Benjamin, Slutsker, Laurence, Agyekum, Alex, Ofori-Anyinam, Opokua, Kaboré, W, Hamad, Ali Said, Doucka, Y, Wasuna, Ruth, Vansadia, Preeti, Otieno, A, Tahita, MC, Savarese, B, Lanaspa, Miguel, Ogutu, B, Gitaka, J, Lang, T, Drakeley, Chris, Issifou, S, Shomari, M, Abdul, O, Otieno, L, Otieno, K, Nyakuipa, D, Kaboré, William, Asante, Isaac, Gesase, Samwel, Cohen, Joe, Aide, P, Shubis, Kafuruki, Ogutu, Bernhards, Agnandji, Selidji Todagbe, Otieno, Lucas, Sambian, David, Kilavo, H, Adjei, S, Greenwood, B, Ansong, Daniel, Lell, Bertrand, Chandramohan, D, Awino, Norbert, Asante, KP, Rettig, T, Adjei, G, Gitaka, Jesse, Carter, Terrell, Juma, Omar, Gondi, S, Ouédraogo, JB, Tinto, H, Lemnge, M, Shomari, Mwanajaa, Guiguemdé, RT, Hoffman, Irving, Mvalo, T, Mtoro, Ali, Schellenberg, David, Quelhas, Diana, Radford, Afiya, Minja, Rose, Lievens, M, Cohen, J, Sorgho, H, Kerubo, Christine, Bawa, J, Theander, Thor, Ahmed, Saumu, Juma, O, Odero, Chris, Vekemans, Johan, Nkomo, Ruthendo, Muturi-Kioi, Vincent, Mvalo, Tisungane, RTS,S Clinical Trials Partnership, Theander, T, Tsofa, Benjamin, Dosoo, David, Ouédraogo, Jean Bosco, Mwangoka, Grace, Kremsner, PG, Jumbe, A, Otieno, W, Boateng, HO, Jongert, E, Rettig, Theresa, Conzelmann, C, Sorgho, Hermann, Flamen, A, Lell, B, Bejon, P, Ouédraogo, Sayouba, Osei-Kwakye, Kingsley, Agbenyega, Tsiri, Owira, Victorine, Nekoye, O, Issifou, Saadou, Muturi-Kioi, V, Ayamba, S, Kariuki, Simon, Methogo, BG, Oneko, Martina, Otieno, Kephas, Olotu, Ally, Lapierre, Didier, Fernandes, José Francisco, Macete, E, Owira, V, Ali, Ali Mohammed, Boahen, Owusu, Minja, R, Oneko, M, Onyango, Agnes Akoth, Leach, A, Liheluka, E, Sylverken, Justice, Lusingu, J, Hamel, Mary J, Salim, N, Vansadia, P, Owusu-Agyei, S, Njuguna, P, Kamthunzi, P, Macete, Eusébio, Mwangoka, G, Asante, Kwaku Poku, Owusu-Agyei, Seth, Fernandes, JF, Lemnge, Martha, Chintedza, J, Nhamuave, A, Ayamba, Samuel, Hamel, MJ, Msika, Albans, Kayan, Kingsley, Leboulleux, D, Alonso, Pedro, Kamthunzi, Portia, Marsh, K, Otieno, Allan, Kerubo, C, Ballou, W Ripley, Nekoye, Otsyula, Lanaspa, M, Shubis, K, Lievens, Marc, Sykes, A, Abossolo, Béatrice Peggy, Lapierre, D, Mandjate, Sofia, Chome, N, Ofori-Anyinam, O, Dosoo, D, Martinson, F, Marsh, Kevin, Urassa, Alwisa Martin, Mahende, Coline, Abdulla, S, Tsofa, B, Ali, AM, Boahen, O, Bassat, Q, Bawa, John, Sandrine, Yara, Osei-Kwakye, K, Peshu, N, Akoo, Pauline, Adjei, Samuel, Njuguna, Patricia, Jumbe, Allan, Williamson, John, Agbenyega, T, Sacarlal, J, Mtoro, A, Leboulleux, Didier, Greenwood, Brian, Malabeja, Anangisye, Wasuna, R, Chilengi, Roma, Schellenberg, D, Nhamuave, Arlindo, Guiguemdé, Robert Tinga, Awino, N, Tinto, Halidou, Tahita, Marc Christian, Mandjate, S, Asante, I, Martinson, Francis, Abossolo, BP, Tanner, M, Williamson, J, Kariuki, S, Machera, F, Kilavo, Hassan, Jones, D, Lusingu, John, Boateng, Harry Owusu, Chintedza, Joseph, Soulanoudjingar, Solange Solmeheim, Lang, Trudie, Sacarlal, Jahit, Gesase, S, Mahende, C, Ouédraogo, S, Bruls, Myriam, Guerra, Y, Msika, A, Soulanoudjingar, SS, Loucq, C, The RTS, S. Clinical Trials Partnership, Sykes, Alma, Agyekum, A, Owusu, L, Vekemans, J, Owusu, Larko, Odero, C, Tanner, Marcel, Laserson, Kayla F, Peshu, Norbert, Savarese, Barbara, Owusu-Ofori, Ruth, Omoto, J, Valea, Innocent, Chilengi, R, Bruls, M, D'Alessandro, Umberto, Onyango, AA, Hoffman, I, Salim, Nahya, Laserson, KF, D'Alessandro, U, Ballou, WR, Nkomo, R, Olotu, A +282 morecore +1 more sourceA Trial of a 7-Valent Pneumococcal Conjugate Vaccine in HIV-Infected Adults. [PDF]
, 2010 BACKGROUND: Streptococcus pneumoniae is a leading and serious coinfection in adults with human immunodeficiency virus (HIV) infection, particularly in Africa.Zijlstra, EE, Molyneux, Malcolm E, White, Sarah A., Mwaiponya, Martin, Mwalukomo, Thandie, Gordon, Stephen, Zijlstra, Eduard E, Longwe, Herbert, French, N, Mwalukomo, T, White, SA, French, Neil, Gordon, SB, Mwaiponya, M, Gilks, CF, Gilks, Charles F, Mwafulirwa, Gershom, Molyneux, Malcolm E., Mwafulirwa, G, Molyneux, ME, Gordon, Stephen B., Gordon, Stephen B, White, Sarah; id_orcid, Longwe, H, Gilks, Charles F., White, Sarah A, Zijlstra, Eduard E. +26 morecore +1 more sourceEvidence of blood stage efficacy with a virosomal malaria vaccine in a Phase IIa clinical trial [PDF]
, 2008 Background
Previous research indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria vaccine.Zurbriggen, R, Gerd Pluschke, Sarah C. Gilbert, Hill, Adrian, Hutchings, Claire, Gilbert Sarah C., Sinden, Robert, Gilbert, Sarah, Pluschke, G, Gilbert, Sarah C., Zurbriggen Rinaldo, Vogel, Denise, Jack L. Williams, Correa, S, Andrews Laura, Okitsu, SL, Westerfeld Nicole, Andrews, Laura, Vogel, D, David W. Porter, Thompson, Fiona, Okitsu, Shinji, Ian Poulton, Todryk, S, Shinji L. Okitsu, Denise Vogel, Dunachie Susanna, Thompson Fiona M., Berthoud, Tamara, Andrews, L, Sinden, R, Porter David W., Pluschke, Gerd, Sarah C Gilbert, Sinden Robert, Poulton Ian, Fiona M Thompson, Berthoud, T, Zurbriggen, Rinaldo, Rinaldo Zurbriggen, Susanna Dunachie, Westerfeld, Nicole, Tamara Berthoud, Todryk, Stephen, Okitsu Shinji L., Hill Adrian V. S., Correa Simon, Berthoud Tamara, Dunachie, S, Westerfeld, N, David W Porter, Nicole Westerfeld, Todryk Stephen, Porter, David, Correa, Simon, Thompson, FM, Pluschke Gerd, Hutchings, C, Poulton, Ian, Hutchings Claire, Williams, JL, Vogel Denise, Shinji L Okitsu, Fiona M. Thompson, Poulton, I, Jack L Williams, Simon Correa, Laura Andrews, Dunachie, Susanna, Adrian V S Hill, Robert Sinden, Porter, DW, Stephen Todryk, Williams, Jack, Claire Hutchings, Williams Jack L. +75 morecore +1 more sourceThe marginal willingness-to-pay for attributes of a hypothetical HIV vaccine [PDF]
, 2012 This paper estimates the marginal willingness-to-pay for attributes of a hypothetical HIV vaccine using discrete choice modeling. We use primary data from 326 respondents from Bangkok and Chiang Mai, Thailand, in 2008–2009, selected using purposive ...Newman, Peter A., Newman, PA, P. A. Newman, S. Roungprakhon, Newman, P.A., Cameron, MP, Scarpa, R., Scarpa, R, Scarpa, Riccardo, Roungprakhon, S, Cameron, Michael P., Cameron, Michael Patrick, Cameron, M.P., Roungprakhon, S., Roungprakhon, Surachet, M. P. Cameron +15 morecore +1 more sourceRandomized, Controlled Trial of the Long Term Safety, Immunogenicity and Efficacy of RTS,S/AS02(D) Malaria Vaccine in Infants Living in a Malaria-Endemic Region. [PDF]
, 2013 The RTS,S/AS malaria candidate vaccine is being developed with the intent to be delivered, if approved, through the Expanded Programme on Immunization (EPI) of the World Health Organization.Machera, Francisca, Abdulla, Salim, Tanner, M., Schellenberg David, Vekemans, J., Richard Kamata, Kamata, Richard, Grace Mwangoka, Kubhoja, S., Leach, Amanda, Villafana Tonya, Dubois Marie-Claude, Sulende Kubhoja, Carter, T, Carter Terrell, Villafana, T, Dubois, M-C, Salim Nahya, Mshinda, H, Dubois, Marie-Claude, Leach, A, Joe Cohen, Salim, N, Kubhoja, Sulende, Vekemans Johan, Salim Abdulla, Mwangoka, G, Carter, T., Juma, O., Mohammed, A., Marcel Tanner, Marie-Claude Dubois, Mshinda Hassan, Marc Lievens, Aebi, Thomas, Kamata, R., Nahya Salim, Ballou, W Ripley, Machera, F., Leach, A., Lievens, Marc, Mohammed Ali, Leach Amanda, Ballou, W. R., W Ripley Ballou, Abdulla, S, Amanda Leach, Kubhoja Sulende, Cohen Joe, Ali Mohammed, Mwangoka Grace, Lievens Marc, Salim, N., Cohen, J., Hassan Mshinda, Abdulla, S., Mohammed, A, Aebi, T, Shomari, M, Mwangoka, G., Schellenberg, D, Cohen, Joe, Schellenberg, D., Machera Francisca, Tanner Marcel, Abdulla Salim, Tanner, M, Carter, Terrell, Juma, Omar, Ballou W Ripley, Omar Juma, Machera, F, Shomari, Mwanajaa, Aebi, T., Schellenberg, David, Mwanajaa Shomari, Lievens, M, Cohen, J, Thomas Aebi, Lievens, M., Juma Omar, Vekemans, J, Juma, O, Vekemans, Johan, Mshinda, Hassan, Tanner, Marcel, Shomari Mwanajaa, Mwangoka, Grace, David Schellenberg, Francisca Machera, Villafana, T., Shomari, M., Mshinda, H., Terrell Carter, Salim, Nahya, Mohammed, Ali, Dubois, M. C., Ballou, WR, Tonya Villafana, Kamata Richard, Kubhoja, S, Aebi Thomas, Johan Vekemans, Kamata, R, Villafana, Tonya +104 morecore +1 more sourceThe Correlated Beta Dose Optimisation Approach: Optimal Vaccine Dosing Using Mathematical Modelling and Adaptive Trial Design [PDF]
, 2022 Mathematical modelling methods and adaptive trial design are likely to be effective for optimising vaccine dose but are not yet commonly used. This may be due to uncertainty with regard to the correct choice of parametric model for dose-efficacy or dose ...Benest, John, Evans, Thomas G, White, Richard G, White, Richard G., Thomas G. Evans, Evans, Thomas G., Sophie Rhodes, Rhodes, Sophie, John Benest, Richard G. White +9 morecore +1 more source