Results 251 to 260 of about 435,241 (348)

Rotavirus A genotype diversity and antigenic profile in Central Ethiopia: implications for rotarix^® vaccine efficacy. [PDF]

Front Microbiol
Redda YT, Adamu H, Bergholm J, Lindahl JF, Blomström AL, Berg M, Sisay Tessema T.   +6 more
europepmc   +1 more source

Nanostructured Lipid Carriers Overcome the Low Immunogenicity of M2e Peptide via Surface Click Chemistry Conjugation, Improving the Anti‐M2e Antibody Response

Advanced NanoBiomed Research, EarlyView.
1) Nanostructured lipid carriers efficiently vectorize low‐immunogenic M2e peptide. 2) M2e peptide conjugation via click chemistry preserves the peptide key epitopes. 3) Forty M2e peptides per nanoparticle are sufficient to induce robust immune responses.
Louis Bourlon, Carole Fournier, Antoine Hoang, Christine Charrat, Alban Lepetitcolin, Jessica Morlieras, Fabrice Navarro, Patrice N. Marche   +7 more
wiley   +1 more source

Lay Understanding of Vaccine Efficacy. [PDF]

J Appl Res Mem Cogn
Butler AE, Chapman GB.
europepmc   +1 more source

A Multiepitope‐Based Lateral Flow Assay for Leprosy Antibodies

Analysis &Sensing, EarlyView.
An innovative lateral flow assay for leprosy diagnosis is based on gold nanoparticles and synthetic Mycobacterium leprae epitopes conjugated to keyhole limpet hemocyanin protein to enhance antibody detection. This strategy provides a rapid, accurate, and low‐cost approach for resource‐limited settings, enabling the early detection of infection. Leprosy
Cristiane Zocatelli‐Ribeiro, Camila dos Anjos Proença, Ana Carolina da Rosa Nogarolli, Ana Fabiele Domakoski Trevisan, Thiago Neves Machado, João Carlos Degraf Muzzi, Larissa Magalhães Alvarenga, Juliana de Moura   +7 more
wiley   +1 more source

Effectiveness of interventions to improve vaccine efficacy: a systematic review and meta-analysis. [PDF]

Syst Rev
S AK, Wasnik A, Gupta L, Ranjan A, Suresh H.   +4 more
europepmc   +1 more source

Optimization and Characterization of Aspirin‐ and Ibuprofen‐Loaded Lipid‐Based Nanoparticle Synthesis for Antibacterial Activity and Cytotoxic Effect

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Lipid‐based nanoparticles (LNPs) are favored for drug delivery because of their low toxicity, high biocompatibility, ability to self‐assemble into nanoparticles, and ability to enhance drug bioavailability, thereby improving drug release modulation and pharmacokinetics.
Gulizar Caliskan, Smyrna Ergonul, Zuhal Naz Cansu, Busra Kaplan   +3 more
wiley   +1 more source

Immune correlates analysis of antibody responses against SARS-CoV-2 variants in the ENSEMBLE vaccine efficacy trial. [PDF]

iScience
Luedtke A, Fong Y, van der Laan L, Heng F, Huang Y, Lu Y, Yu C, Carpp LN, Roels S, Le Gars M, Van Roey GA, Stieh DJ, Van Dromme I, Kenny A, Carone M, Hyrien O, Ayala V, Jayashankar L, Castellino F, Amoa-Awua O, Basappa M, Flach B, Lin BC, Moore C, Naisan M, Naqvi M, Narpala S, O'Connell S, Mueller A, Serebryannyy L, Castro M, Wang J, Dziubla G, Randhawa AK, Andrasik MP, Hendriks J, Truyers C, Struyf F, Schuitemaker H, Douoguih M, Kublin JG, Corey L, Neuzil KM, Bekker LG, Garrett N, Cardoso SW, DelaFontaine P, Magaret CA, Vingerhoets J, Casapia M, Losso MH, Little SJ, Gaur A, Swann E, Petropoulos CJ, McDermott AB, Sadoff J, Gray GE, Grinsztejn B, Goepfert PA, Follmann D, Roychoudhury P, Greninger AL, Koup RA, Donis RO, Gilbert PB, Immune Assays Team, Coronavirus Vaccine Prevention Network (CoVPN)/ENSEMBLE Team, United States Government (USG)/CoVPN Biostatistics Team.   +68 more
europepmc   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

Animal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng, Xuyan Xiang, Xinyu Qi, Hanrong Zhou, Peiyu Xiao, Fandan Meng, Tongqing An, Haiwei Wang   +7 more
wiley   +1 more source

Anti-tumor vaccine efficacy depends on adjuvant type and associates with induced IgG subclass and glycosylation profiles. [PDF]

Exp Hematol Oncol
Lehrian S, Wasynczuk A, Petry J, Guderian M, Nouta J, Buhre JS, Lunding HB, Köcher P, Schumacher HF, Dühring L, Kurwahn K, Manzhula K, Manz R, Bartsch YC, Wuhrer M, Ehlers M.   +15 more
europepmc   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source