Results 21 to 30 of about 32,135 (260)

Characterizing infection of B cells with wild-type and vaccine strains of measles virus

iScience, 2023
Summary: Acute infection with measles virus (MeV) causes transient immunosuppression often leading to secondary infections. MeV infection of B lymphocytes results in changes in the antibody repertoire and memory B cell populations for which the mechanism
Logan Melot, Bettina Bankamp, Paul A. Rota, Melissa M. Coughlin   +3 more
doaj   +1 more source

Vaccination strategies for the prevention of meningococcal disease [PDF]

Human Vaccines & Immunotherapeutics, 2018
Routine prophylactic vaccination and mass vaccination strategies have been used to control both endemic and epidemic disease caused by Neisseria meningitidis globally. This review discusses real-world examples of these vaccination strategies, their implementation, and outcomes of these efforts, with the overall goal of providing insights on how to ...
Scott Vuocolo, Paul Balmer, William C. Gruber, Kathrin U. Jansen, Annaliesa S. Anderson, John L. Perez, Laura J. York   +6 more
openaire   +3 more sources

Vaccine effectiveness against mild and severe covid-19 in pregnant individuals and their infants in England: test negative case-control study

BMJ Medicine
Objective To estimate real world vaccine effectiveness against symptomatic disease and hospital admission with the delta and omicron variants of the SARS-CoV-2 virus in pregnant individuals, and to estimate the protection conferred by previous infection ...
Shamez Ladhani, Nick Andrews, Mary Ramsay, Julia Stowe, Jamie Lopez Bernal, Freja C M Kirsebom, Anna A Mensah, Helen Julia Campbell   +7 more
doaj   +1 more source

Emergence of vaccine-derived poliovirus type 2 after using monovalent type 2 oral poliovirus vaccine in an outbreak response, Philippines

Western Pacific Surveillance and Response, 2022
Objective: In response to an outbreak of circulating vaccine-derived poliovirus (cVDPV) type 2 in the Philippines in 2019–2020, several rounds of supplementary immunization activities using the monovalent type 2 oral poliovirus vaccine (OPV) were ...
SweetC B Alipon, Yoshihiro Takashima, Tigran Avagyan, Varja Grabovac, Syeda Kanwal Aslam, Benjamin Bayutas, Josephine Logronio, Xiaojun Wang, Achyut Shrestha, Sukadeo Neupane, Maria Concepcion Roces, Lea Necitas Apostol, Nemia Sucaldito   +12 more
doaj   +1 more source

Measles vaccination coverage among five‐year‐old children: implications for disease elimination in Australia

Australian and New Zealand Journal of Public Health, 2003
Objectives:To (i) assess under‐reporting of measles‐mumps‐rubella (MMR) vaccinations to the Australian Childhood Immunisation Register (ACIR); (ii) estimate MMR coverage among five‐year‐old children and the proportion immune to measles infection; (iii ...
Glenda L. Lawrence, C. Raina MacIntyre, Brynley P. Hull, Peter B. McIntyre   +3 more
doaj   +1 more source

Parents’ and teachers’ attitudes to and experiences of the implementation of COVID-19 preventive measures in primary and secondary schools following reopening of schools in autumn 2020: a descriptive cross-sectional survey

BMJ Open, 2022
Objective To assess implementation and ease of implementation of control measures in schools as reported by staff and parents.Design A descriptive cross-sectional survey.Setting Staff and parents/guardians of the 132 primary schools and 19 secondary ...
Shamez N Ladhani, Chris Bonell, Samuel E Jones, Meaghan Kall, Joanne Beckmann, Sinéad M Langan, Zahin Amin-Chowdhury, Felicity Aiano, Joanna Garstang, Shazaad Ahmad, Andrew J Brent, Neisha Sundaram, James Hargreaves, Georgina Ireland, Marta Bertran, Annabel Powell, Bernadette E Brent, Frances Baawuah, Ifeanychukwu Okike   +18 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Immunisation coverage in Australia corrected for under‐reporting to the Australian Childhood Immunisation Register

Australian and New Zealand Journal of Public Health, 2003
Objective: To assess the level of underreporting to the Australian Childhood Immunisation Register (ACIR) and the resulting underestimation of national immunisation coverage using ACIR data, and to correct national immunisation estimates for under ...
Brynley P. Hull, Glenda L. Lawrence, C. Raina MacIntyre, Peter B. McIntyre   +3 more
doaj   +1 more source

Vaccine-Preventable Diseases Requiring Hospitalization [PDF]

Pediatrics, 2017
BACKGROUND: Plain children often have lower immunization rates than non-Plain children. Penn State Health Children’s Hospital is a tertiary medical center with large nearby Plain (Amish and Mennonite) communities. We sought to describe the characteristics of children hospitalized with vaccine-preventable diseases ...
Gregory, Williamson, Bilaal, Ahmed, Parvathi S, Kumar, Barbara E, Ostrov, Jessica E, Ericson   +4 more
openaire   +2 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source