Results 31 to 40 of about 32,135 (260)

Addressing Determinants of Immunization Inequities Requires Objective Tools to Devise Local Solutions

Vaccines, 2023
Universal immunization substantially reduces morbidity and mortality from vaccine-preventable diseases. In recent years, routine immunization coverage has varied considerably among countries across the WHO European Region, and among different populations
Siddhartha Sankar Datta, Federico Martinón-Torres, Nino Berdzuli, Niyazi Cakmak, Michael Edelstein, Simon Cottrell, Mark Muscat   +6 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Progress and Challenges in Measles and Rubella Elimination in the WHO European Region

Vaccines
The elimination of both measles and rubella remains a priority for all 53 Member States of the World Health Organization (WHO) European Region. To provide an update on the epidemiological status of measles and rubella in the Region, we reviewed ...
Mark Muscat, Myriam Ben Mamou, Catharina Reynen-de Kat, Dragan Jankovic, José Hagan, Simarjit Singh, Siddhartha Sankar Datta   +6 more
doaj   +1 more source

Genomic characterization of Haemophilus influenzae: a focus on the capsule locus

BMC Genomics, 2019
Background Haemophilus influenzae (Hi) can cause invasive diseases such as meningitis, pneumonia, or sepsis. Typeable Hi includes six serotypes (a through f), each expressing a unique capsular polysaccharide.
Caelin C. Potts, Nadav Topaz, Lorraine D. Rodriguez-Rivera, Fang Hu, How-Yi Chang, Melissa J. Whaley, Susanna Schmink, Adam C. Retchless, Alexander Chen, Edward Ramos, Gregory H. Doho, Xin Wang   +11 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

The impact of multiplex panel testing on ascertainment of pertussis-attributable, non-infant deaths: national surveillance from England

Journal of Clinical Microbiology
Understanding the burden of pertussis and pertussis-related mortality is important in enabling a better understanding of population vulnerability and supporting vaccination program planning.
Catherine Sandford Alber, Emer Cullen, Sonia Ribeiro, David J. Litt, Gayatri Amirthalingam, Helen Campbell, Sharif A. Ismail   +6 more
doaj   +1 more source

BMScan: using whole genome similarity to rapidly and accurately identify bacterial meningitis causing species

BMC Infectious Diseases, 2018
Background Bacterial meningitis is a life-threatening infection that remains a public health concern. Bacterial meningitis is commonly caused by the following species: Neisseria meningitidis, Streptococcus pneumoniae, Listeria monocytogenes, Haemophilus ...
Nadav Topaz, Dave Boxrud, Adam C. Retchless, Megan Nichols, How-Yi Chang, Fang Hu, Xin Wang   +6 more
doaj   +1 more source

The Impact of War on Vaccine Preventable Diseases [PDF]

Materia Socio Medica, 2014
During the war in Bosnia and Herzegovina, which lasted from 1992-1995, the functioning of all sectors was disturbed, including the health sector. The priority of the heath sector was treatment and less attention was paid to prevention, and this applies also to the Program of implementation of obligatory immunization, as one of the most important ...
Obradovic, Zarema, Balta, Snjezana, Obradovic, Amina, Mesic, Salih   +3 more
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Comparison of traditional culture and molecular qPCR for detection of simultaneous carriage of multiple pneumococcal serotypes in African children

Scientific Reports, 2017
S. pneumoniae is a common colonizer of the human nasopharynx in high income and low-middle income countries. Due to limitations of standard culture methods, the prevalence of concurrent colonization with multiple serotypes is unclear.
Courtney P. Olwagen, Peter V. Adrian, Shabir A. Madhi   +2 more
doaj   +1 more source