Results 51 to 60 of about 66,881 (311)

Committing to Child Survival: A Promise Renewed Progress Report 2015 [PDF]

open access: yes, 2015
Twenty-five years ago this month, when the Convention on the Rights of the Child came into force, the world made a promise to its children. It was a promise to do everything we could to keep them alive, to keep them healthy, and to help them realize ...

core  

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

open access: yesAdvanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao   +11 more
wiley   +1 more source

Infection-acquired versus vaccine-acquired immunity in an SIRWS model [PDF]

open access: yes, 2017
Despite high vaccine coverage, pertussis has re-emerged as a public health concern in many countries. One hypothesis posed for re-emergence is the waning of immunity.
Campbell, Patricia T   +4 more
core   +2 more sources

PRELIVE: A Framework for Predicting Lipid Nanoparticles In Vivo Efficacy and Reducing Reliance on Animal Testing

open access: yesAdvanced Functional Materials, EarlyView.
PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy   +3 more
wiley   +1 more source

Evaluation of Immunization Policies for PeaceKeeping Missions [PDF]

open access: yes, 2017
This article first examines data bases available to assess the risk of vaccine-preventable diseases (VPD). In the second part, immunization recommendations and practices are briefly evaluated in view of the risk of exposure to VPD and of the efficacy and
Desaules, Madeleine   +3 more
core  

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

Reclaiming momentum: The Essential Programme on Immunization in the journey to 2030 and beyond

open access: yesHuman Vaccines & Immunotherapeutics
Fifty-one years after the launch of the Expanded Programme on Immunization – now rebranded as the Essential Programme on Immunization – routine vaccination remains the most transformative public health intervention, preventing more than 154 million ...
Charles S. Wiysonge   +5 more
doaj   +1 more source

Acute flaccid paralysis with anterior myelitis - California, June 2012-June 2014. [PDF]

open access: yes, 2014
In August 2012, the California Department of Public Health (CDPH) was contacted by a San Francisco Bay area clinician who requested poliovirus testing for an unvaccinated man aged 29 years with acute flaccid paralysis (AFP) associated with anterior ...
Ayscue, Patrick   +17 more
core   +1 more source

Advances in vaccines: revolutionizing disease prevention

open access: yesScientific Reports, 2023
Vaccines have revolutionized modern medicine by preventing infectious diseases and safeguarding public health. This Collection showcases cutting-edge research on advancements in vaccine development and their impact on disease prevention. The papers presented here report various facets of vaccine efficacy, immunological responses, and design, providing ...
openaire   +3 more sources

Influenza vaccines for preventing cardiovascular disease [PDF]

open access: yesSao Paulo Medical Journal, 2015
This is an update of the original review published in 2008. The risk of adverse cardiovascular outcomes is increased with influenza-like infection, and vaccination against influenza may improve cardiovascular outcomes.To assess the potential benefits of influenza vaccination for primary and secondary prevention of cardiovascular disease.We searched the
Christine Clar   +4 more
openaire   +5 more sources

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