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Design of live attenuated bacterial vaccines based on D-glutamate auxotrophy
Nature Communications, 2017 Vaccine development is a priority for global health due to the growing multidrug resistance in bacteria. D-glutamate synthesis is essential for bacterial cell wall formation.
Maria P. Cabral +6 more
semanticscholar +1 more source
Vaccines, 2022 Influenza is a vaccine preventable disease and vaccination remains the most effective method of controlling the morbidity and mortality of seasonal influenza, especially with respect to risk groups.
C. Trombetta +4 more
semanticscholar +1 more source
EXPERIMENTAL MEASLES VACCINES: A RESEARCH TOOL IN VACCINATION EVENTS
Медицинская иммунология, 2014 . The review article considers different variants of measles vaccine that may be classified into two groups, i.e., vaccines that do not contain viable measles virus, and attenuated measles vaccines which could be employed in unusual manner.The first ...
V. A. Liashenko
doaj +1 more source
Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]
, 2019 Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Barclay WR +8 more
core +1 more source
Recent progress on gene-deleted live-attenuated African swine fever virus vaccines
npj VaccinesAfrican Swine Fever (ASF) is a highly lethal viral disease in swine, with mortality rates approaching 100%. The disease has spread to many swine-producing countries, leading to significant economic losses and adversely impacting global food security ...
Hiep L. X. Vu, D. S. McVey
semanticscholar +1 more source
An Overview of Influenza Viruses and Vaccines
Vaccines, 2021 Influenza remains one of the major public health concerns because it causes annual epidemics and can potentially instigate a global pandemic. Numerous countermeasures, including vaccines and antiviral treatments, are in use against seasonal influenza ...
R. Nuwarda, A. Alharbi, Veysel Kayser
semanticscholar +1 more source
Live Attenuated Varicella Vaccine
The Journal of Pediatrics, 1984 Live attenuated varicella vaccine will in all probability soon be licensed in the United States for immunization of healthy children and adults and certain immunocompromised children. This vaccine can be expected to protect susceptibles from varicella (or to modify it) in those subsequently exposed to the wild virus.
openaire +6 more sources
Developing live vaccines against plague
Journal of Infection in Developing Countries, 2011 Three great plague pandemics caused by the gram-negative bacterium Yersinia pestis have killed nearly 200 million people and it has been linked to biowarfare in the past. Plague is endemic in many parts of the world.
Wei Sun +2 more
doaj +1 more source
Roadblocks to translational challenges on viral pathogenesis. [PDF]
, 2013 Distinct roadblocks prevent translating basic findings in viral pathogenesis into therapies and implementing potential solutions in the clinic. An ongoing partnership between the Volkswagen Foundation and Nature Medicine resulted in an interactive ...
Deeks, Steven +4 more
core +1 more source
Nature Microbiology, 2023 Comparison of mucosal and systemic immunity after vaccination with the live-attenuated vaccine sCPD9, mRNA vaccine BNT162b2 or an adenovirus-vectored vaccine following SARS-CoV-2 challenge in hamsters. Vaccines play a critical role in combating the COVID-
G. Nouailles +34 more
semanticscholar +1 more source