Results 51 to 60 of about 1,439,979 (204)

Design of live attenuated bacterial vaccines based on D-glutamate auxotrophy

Nature Communications, 2017
Vaccine development is a priority for global health due to the growing multidrug resistance in bacteria. D-glutamate synthesis is essential for bacterial cell wall formation.
Maria P. Cabral, Patricia García, A. Beceiro, Carlos Rumbo, Astrid Pérez, M. Moscoso, G. Bou   +6 more
semanticscholar   +1 more source

The Shigella Vaccines Pipeline

Vaccines, 2022
Shigella is the leading cause of global diarrheal deaths that currently lacks a licensed vaccine. Shigellosis drives antimicrobial resistance and leads to economic impact through linear growth faltering.
C. MacLennan, Stephanie Grow, Lyou-fu Ma, A. Steele   +3 more
semanticscholar   +1 more source

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021–22 Influenza Season

MMWR Recommendations and Reports, 2021
Summary This report updates the 2020–21 recommendations of the Advisory Committee on Immunization Practices (ACIP) regarding the use of seasonal influenza vaccines in the United States (MMWR Recomm Rep 2020;69[No. RR-8]).
L. Grohskopf, E. Alyanak, J. Ferdinands, K. Broder, L. Blanton, H. Talbot, A. Fry   +6 more
semanticscholar   +1 more source

Systems Vaccinology for a Live Attenuated Tularemia Vaccine Reveals Unique Transcriptional Signatures That Predict Humoral and Cellular Immune Responses

Vaccines, 2019
Background: Tularemia is a potential biological weapon due to its high infectivity and ease of dissemination. This study aimed to characterize the innate and adaptive responses induced by two different lots of a live attenuated tularemia vaccine and ...
Muktha S. Natrajan, Nadine Rouphael, Lilin Lai, Dmitri Kazmin, Travis L. Jensen, David S. Weiss, Chris Ibegbu, Marcelo B. Sztein, William F. Hooper, Heather Hill, Evan J. Anderson, Robert Johnson, Patrick Sanz, Bali Pulendran, Johannes B. Goll, Mark J. Mulligan   +15 more
doaj   +1 more source

2015–2016 Vaccine Effectiveness of Live Attenuated and Inactivated Influenza Vaccines in Children in the United States

Clinical Infectious Diseases, 2017
This test-negative case-control study showed live attenuated influenza vaccine and inactivated influenza vaccine were effective against any influenza in 2015–2016.
K. Poehling, H. Caspard, T. R. Peters, E. Belongia, B. Congeni, M. Gaglani, M. Griffin, Stephanie A. Irving, Poornima K Kavathekar, H. McLean, A. Naleway, K. Ryan, H. Talbot, C. Ambrose   +13 more
semanticscholar   +1 more source

Single-Dose Immunogenic DNA Vaccines Coding for Live-Attenuated Alpha- and Flaviviruses

Viruses
Single-dose, immunogenic DNA (iDNA) vaccines coding for whole live-attenuated viruses are reviewed. This platform, sometimes called immunization DNA, has been used for vaccine development for flavi- and alphaviruses.
Peter Pushko, Igor S. Lukashevich, Dylan M. Johnson, Irina Tretyakova   +3 more
doaj   +1 more source

Influenza Vaccination Strategies: Comparing Inactivated and Live Attenuated Influenza Vaccines

Vaccines, 2015
Influenza is a major respiratory pathogen causing annual outbreaks and occasional pandemics. Influenza vaccination is the major method of prophylaxis.
S. Sridhar, K. Brokstad, R. Cox
semanticscholar   +1 more source

Live-attenuated vaccination in patients with inflammatory bowel disease while continuing or after elective switch to vedolizumab [PDF]

Intestinal Research
Background/Aims Vedolizumab (VDZ) is a gut-selective agent with a favorable safety profile. We aimed to assess the feasibility of elective switch from other advanced therapies to VDZ and subsequent live-attenuated vaccination while continuing VDZ in ...
Hisashi Shiga, Hiroshi Nagai, Yusuke Shimoyama, Takeo Naito, Rintaro Moroi, Yoichi Kakuta, Yoshitaka Kinouchi, Atsushi Masamune   +7 more
doaj   +1 more source

Current Advances in Zika Vaccine Development

Vaccines, 2022
Zika virus (ZIKV), an emerging arthropod-borne flavivirus, was first isolated in Uganda in 1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated with a dramatic burden worldwide. Since then, interventions to reduce the
Yuchen Wang, Lin Ling, Zilei Zhang, Alejandro Marin-Lopez   +3 more
doaj   +1 more source

Review: Vaccines and Vaccination against Lumpy Skin Disease

Vaccines, 2021
The geographical distribution of lumpy skin disease (LSD), an economically important cattle disease caused by a capripoxvirus, has reached an unprecedented extent.
E. Tuppurainen, K. Dietze, J. Wolff, H. Bergmann, D. Beltrán-Alcrudo, A. Fahrion, C. Lamien, F. Busch, C. Sauter-Louis, F. Conraths, K. De Clercq, B. Hoffmann, S. Knauf   +12 more
semanticscholar   +1 more source