Results 41 to 50 of about 470,609 (301)

Coinfection in the host can result in functional complementation between live vaccines and virulent virus

Virulence, 2022
One of the greatest achievements of the last century is the development of vaccines against viral diseases. Vaccines are essential for battling infectious diseases and many different formulations are available, including live attenuated vaccines. However,
Huai Xu, Andrea L. Krieter, Nagendraprabhu Ponnuraj, Yvette (Yung-Tien) Tien, Taejoong Kim, Keith W. Jarosinski   +5 more
doaj   +1 more source

Comparison of the efficacy of autogenous inactivated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccines with that of commercial vaccines against homologous and heterologous challenges

BMC Veterinary Research, 2012
Background The porcine reproductive and respiratory syndrome virus (PRRSV) is a rapidly evolving pathogen of swine. At present, there is a high demand for safe and more effective vaccines that can be adapted regularly to emerging virus variants. A recent
Geldhof Marc F, Vanhee Merijn, Van Breedam Wander, Van Doorsselaere Jan, Karniychuk Uladzimir U, Nauwynck Hans J   +5 more
doaj   +1 more source

Current status of vaccine research, development, and challenges of vaccines for Mycoplasma gallisepticum

Poultry Science, 2020
Mycoplasma gallisepticum (MG) is an important avian pathogen that causes significant economic losses in the poultry industry. Surprisingly, the limited protection and adverse reactions caused by the vaccines, including live vaccines, bacterin-based ...
Muhammad Ishfaq, Wanying Hu, Mohammad Zeb Khan, Ijaz Ahmad, Wenxin Guo, Jichang Li   +5 more
doaj   +1 more source

Mucosal Immunization Against Pertussis: Lessons From the Past and Perspectives

Frontiers in Immunology, 2021
BackgroundCurrent vaccination strategies against pertussis are sub-optimal. Optimal protection against Bordetella pertussis, the causative agent of pertussis, likely requires mucosal immunity.
Violaine Dubois, Camille Locht
doaj   +1 more source

Systems Vaccinology for a Live Attenuated Tularemia Vaccine Reveals Unique Transcriptional Signatures That Predict Humoral and Cellular Immune Responses

Vaccines, 2019
Background: Tularemia is a potential biological weapon due to its high infectivity and ease of dissemination. This study aimed to characterize the innate and adaptive responses induced by two different lots of a live attenuated tularemia vaccine and ...
Muktha S. Natrajan, Nadine Rouphael, Lilin Lai, Dmitri Kazmin, Travis L. Jensen, David S. Weiss, Chris Ibegbu, Marcelo B. Sztein, William F. Hooper, Heather Hill, Evan J. Anderson, Robert Johnson, Patrick Sanz, Bali Pulendran, Johannes B. Goll, Mark J. Mulligan   +15 more
doaj   +1 more source

Comparative evaluation of lumpy skin disease virus-based live attenuated vaccines [PDF]

, 2021
Vaccines form the cornerstone of any control, eradication and preventative strategy and this is no different for lumpy skin disease. However, the usefulness of a vaccine is determined by a multiplicity of factors which include stability, efficiency ...
De Leeuw, Ilse, Willem Van Campe, L. Mostin, Venter, Estelle Hildegard, W. Van Campe, Estelle Venter, Tuppurainen, Eeva, Van Campe, Willem, E.S.M. Tuppurainen, Kris De Clercq, E. Venter, C. Saegerman, Ilse De Leeuw, Claude Saegerman, Haegeman, Andy, Saegerman, Claude, Aerts, Laetitia, A. Haegeman, Laetitia Aerts, Campe, Willem Van, I. De Leeuw, Laurent Mostin, Mostin, Lauren, Venter, Estelle, De Leeuw, Lise, Eeva Tuppurainen, De Clercq, Kris, Mostin, Laurent, K. De Clercq, Andy Haegeman, L. Aerts   +30 more
core   +1 more source

Blood B Cell Depletion Reflects Immunosuppression Induced by Live-Attenuated Infectious Bursal Disease Vaccines

Frontiers in Veterinary Science, 2022
Immunosuppression in poultry production is a recurrent problem worldwide, and one of the major viral immunosuppressive agents is Infectious Bursal Disease Virus (IBDV). IBDV infections are mostly controlled by using live-attenuated vaccines.
Céline Courtillon, Chantal Allée, Michel Amelot, Alassane Keita, Stéphanie Bougeard, Sonja Härtle, Jean-Claude Rouby, Nicolas Eterradossi, Sebastien Mathieu Soubies   +8 more
doaj   +1 more source

Glyceraldehyde-3-phosphate dehydrogenase common peptides of listeria monocytogenes, mycobacterium marinum and streptococcus pneumoniae as universal vaccines [PDF]

, 2021
Universal vaccines can be prepared with antigens common to different pathogens. In this regard, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a common virulence factor among pathogenic bacteria of the genera Listeria, Mycobacterium and ...
Del Molino-Bernal, I. Concepción Pérez, Torres-Rodriguez, Paula, Calvo-Montes, Jorge, David Salcines-Cuevas, Pérez Del Molino-Bernal, Concepción, Ricardo Calderón-Gonzalez, Manuel Fresno, Álvarez-Domínguez, Carmen, Teran-Navarro, Héctor, Fresno, Manuel, Raquel Tobes, Molino-Bernal, I Concepción Pérez Del, Paula Torres-Rodriguez, Carmen Alvarez-Dominguez, I. Concepción Pérez Del Molino-Bernal, Salcines-Cuevas, David, Fresno Escudero, Manuel, Pérez Del Molino Bernal, I. Concepción, Hector Terán-Navarro, Yañez-Diaz, Sonsoles, Jorge Calvo-Montes, Sonsoles Yañez-Diaz, Calderón-González, Ricardo, Tobes, Raquel   +23 more
core   +1 more source

Current Advances in Zika Vaccine Development

Vaccines, 2022
Zika virus (ZIKV), an emerging arthropod-borne flavivirus, was first isolated in Uganda in 1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated with a dramatic burden worldwide. Since then, interventions to reduce the
Yuchen Wang, Lin Ling, Zilei Zhang, Alejandro Marin-Lopez   +3 more
doaj   +1 more source

Live Attenuated Varicella Vaccine

The Journal of Pediatrics, 1984
Live attenuated varicella vaccine will in all probability soon be licensed in the United States for immunization of healthy children and adults and certain immunocompromised children. This vaccine can be expected to protect susceptibles from varicella (or to modify it) in those subsequently exposed to the wild virus.
openaire   +6 more sources