Results 21 to 30 of about 82,320 (302)

Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes [PDF]

, 2008
Difficulties with inducing sterile and long lasting protective immunity against malaria with subunit vaccines has renewed interest in vaccinations with attenuated <i>Plasmodium</i> parasites.
Melissa R van Dijk, Ben C L van Schaijk, Geert-Jan van Gemert, Yalaoui Samir, Schaijk, B.C.L. van, Waters, A.P., van Gemert, G. J., Franetich Jean-Francois, Samir Yalaoui, Shahid M Khan, van de Vegte-Bolmera, M., Silvie, O., Hoffman, S. L., Franetich, J.F., van Gemert Geert-Jan, Janse, C.J., Vegte-Bolmer, M.G. van de, Yalaouic, S., Khan, S. M., Chris J Janse, Stephen L Hoffman, Sauerwein Robert W., Silvie Olivier, Sauerwein, R. W., Robert W Sauerwein, Andrew P Waters, Hoffman, S.L., van Dijk, M. R., Waters Andrew P., Sauerwein, R.W., Jean-Francois Franetich, Gemert, G.J.A. van, van de Vegte-Bolmer Marga, Khan, S.M., Olivier Silvie, Mazier, D., Gegoc, A., Gego, A., Khan Shahid M., Franetich, J. F., Dijk, M.R. van, Dominique Mazier, Audrey Gego, Yalaoui, S., Waters, A. P., Janse, C. J., van Schaijk Ben C. L., van Dijk Melissa R., van Schaijk, B. C. L., Janse Chris J., Gego Audrey, Mazier Dominique, Marga van de Vegte-Bolmer, Hoffman Stephen L.   +53 more
core   +1 more source

Generation and characterization of chimeric Tembusu viruses containing pre-membrane and envelope genes of Japanese encephalitis virus

Frontiers in Microbiology, 2023
Since its outbreak in 2010, Tembusu virus (TMUV) has spread widely throughout China and Southeast Asia, causing significant economic losses to the poultry industry.
Bangfeng Xu, Xingpo Liu, Dawei Yan, Qiaoyang Teng, Chunxiu Yuan, Zhifei Zhang, Qinfang Liu, Zejun Li   +7 more
doaj   +1 more source

Attenuated Vaccines for Augmented Immunity [PDF]

Cell Host & Microbe, 2017
Live attenuated vaccines are more immunogenic and have the capacity to elicit long-lasting immune responses. In two recent studies, Wang et al. (2017) and Si et al. (2016) describe strategies for the generation of live attenuated influenza viruses, which elicited robust humoral, mucosal, and cellular immunity against diverse virus strains.
Stylianos, Bournazos, Jeffrey V, Ravetch
openaire   +2 more sources

Vaccines for cholera control: does herd immunity play a role. [PDF]

, 2007
The author discusses a new study that mathematically simulated different vaccine coverage levels in the Matlab region of Bangladesh using a historic vaccine trial ...
Lorenz von Seidlein, von Seidlein Lorenz, von Seidlein, Lorenz   +2 more
core   +1 more source

Malaria vaccine research and development: the role of the WHO MALVAC committee. [PDF]

, 2013
The WHO Malaria Vaccine Advisory Committee (MALVAC) provides advice to WHO on strategic priorities, activities and technical issues related to global efforts to develop vaccines against malaria.
Vasee S Moorthy, Graham V Brown, Geoffrey AT Targett, Targett, Geoffrey AT, Brown, GV, Moorthy, Vasee S, Brown, Graham V, Geoffrey AT Targett, Moorthy, VS, Targett, GA   +9 more
core   +1 more source

Comparative evaluation of lumpy skin disease virus-based live attenuated vaccines [PDF]

, 2021
Vaccines form the cornerstone of any control, eradication and preventative strategy and this is no different for lumpy skin disease. However, the usefulness of a vaccine is determined by a multiplicity of factors which include stability, efficiency ...
De Leeuw, Ilse, Willem Van Campe, L. Mostin, Venter, Estelle Hildegard, W. Van Campe, Estelle Venter, Tuppurainen, Eeva, Van Campe, Willem, E.S.M. Tuppurainen, Kris De Clercq, E. Venter, C. Saegerman, Ilse De Leeuw, Claude Saegerman, Haegeman, Andy, Saegerman, Claude, Aerts, Laetitia, A. Haegeman, Laetitia Aerts, Campe, Willem Van, I. De Leeuw, Laurent Mostin, Mostin, Lauren, Venter, Estelle, De Leeuw, Lise, Eeva Tuppurainen, De Clercq, Kris, Mostin, Laurent, K. De Clercq, Andy Haegeman, L. Aerts   +30 more
core   +1 more source

New Points of Departure for More Global Influenza Vaccine Use

Vaccines, 2020
Each year, influenza causes a significant acute respiratory disease burden. In addition, influenza pandemics periodically occur. Annual vaccination is the best tool for influenza prevention, but its effectiveness can vary from year to year.
Irina Kiseleva
doaj   +1 more source

Coinfection in the host can result in functional complementation between live vaccines and virulent virus

Virulence, 2022
One of the greatest achievements of the last century is the development of vaccines against viral diseases. Vaccines are essential for battling infectious diseases and many different formulations are available, including live attenuated vaccines. However,
Huai Xu, Andrea L. Krieter, Nagendraprabhu Ponnuraj, Yvette (Yung-Tien) Tien, Taejoong Kim, Keith W. Jarosinski   +5 more
doaj   +1 more source

LC16m8: An attenuated smallpox vaccine

Vaccine, 2006
The frequency of moderate to severe adverse reactions associated with smallpox vaccines currently stockpiled in the US, and the continued threat of bioterrorism have prompted the development of effective vaccines with improved safety profiles. LC16m8, an attenuated, replicating smallpox vaccine derived from the Lister strain of vaccinia, is currently ...
Kenner, Julie, Cameron, Fiona, Empig, Cyril, Jobes, David V., Gurwith, Marc   +4 more
openaire   +2 more sources

Rational Development of Live-Attenuated Zika Virus Vaccines

Pathogens, 2023
Zika virus (ZIKV), a re-emerging mosquito-borne flavivirus, has caused outbreaks in Africa, Asia, the Pacific, and, more recently, in the Americas. ZIKV has been associated with the neurological autoimmune disorder Guillain–Barre syndrome in adults and ...
Awadalkareem Adam, Christy Lee, Tian Wang   +2 more
doaj   +1 more source