Results 11 to 20 of about 470,609 (301)

MicroRNA-Attenuated Virus Vaccines [PDF]

Non-coding RNA, 2018
Live-attenuated vaccines are the most effective way to establish robust, long-lasting immunity against viruses. However, the possibility of reversion to wild type replication and pathogenicity raises concerns over the safety of these vaccines. The use of
Ryan Langlois, Elizabeth J Fay
exaly   +6 more sources

Rational Design of Live-Attenuated Vaccines against Herpes Simplex Viruses

Viruses, 2021
Diseases caused by human herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) affect millions of people worldwide and range from fatal encephalitis in neonates and herpes keratitis to orofacial and genital herpes, among other manifestations.
Brent A. Stanfield, Konstantin G. Kousoulas, Agustin Fernandez, Edward Gershburg   +3 more
doaj   +2 more sources

Single-Dose Immunogenic DNA Vaccines Coding for Live-Attenuated Alpha- and Flaviviruses

Viruses
Single-dose, immunogenic DNA (iDNA) vaccines coding for whole live-attenuated viruses are reviewed. This platform, sometimes called immunization DNA, has been used for vaccine development for flavi- and alphaviruses.
Peter Pushko, Igor S. Lukashevich, Dylan M. Johnson, Irina Tretyakova   +3 more
doaj   +2 more sources

Leveraging Beneficial Off-Target Effects of Live-Attenuated Rotavirus Vaccines [PDF]

Vaccines, 2022
Following the introduction of live-attenuated rotavirus vaccines in many countries, a notable reduction in deaths and hospitalisations associated with diarrhoea in children
Prisca Benedicto-Matambo, Julie E. Bines, Chikondi Malamba-Banda, Isaac T. Shawa, Kayla Barnes, Arox W. Kamng’ona, Daniel Hungerford, Kondwani C. Jambo, Miren Iturriza-Gomara, Nigel A. Cunliffe, Katie L. Flanagan, Khuzwayo C. Jere   +11 more
doaj   +2 more sources

Natural Attenuated Vaccines for Pasteurella multocida

Biology
Pasteurella multocida is capable of infecting various animal species, causing hemorrhagic septicemia or infectious pneumonia, and it is widely prevalent and pathogenic worldwide.
Qingyuan Xu, Lijun Guan, Yun Xue, Zhanqin Zhao   +3 more
doaj   +2 more sources

Live-Attenuated Vaccines in Pediatric Solid Organ Transplant

Vaccines
Measles, mumps, rubella (MMR), and varicella incidence rates have increased due to the delayed vaccination schedules of children secondary to the COVID-19 pandemic. Decreased herd immunity creates a risk for immunocompetent children and immunocompromised
Christopher Hartley, Tina Thomas, Sara Kathryn Smith, Wikrom Karnsakul   +3 more
doaj   +2 more sources

LIVE ATTENUATED VACCINES FOR THE IMMUNOPROPHYLAXIS [PDF]

Инфекция и иммунитет, 2017
The review focuses on the history of the production of live antiviral vaccines and their use for the prevention of infectious diseases. It was noted that before the beginning of the 20th century, only three live vaccines were developed and put into ...
O. A. Shamsutdinova
doaj   +2 more sources

Live Attenuated Vaccines against Tuberculosis: Targeting the Disruption of Genes Encoding the Secretory Proteins of Mycobacteria

Vaccines
Tuberculosis (TB), a chronic infectious disease affecting humans, causes over 1.3 million deaths per year throughout the world. The current preventive vaccine BCG provides protection against childhood TB, but it fails to protect against pulmonary TB ...
Raja Veerapandian, Shrikanth S. Gadad, Chinnaswamy Jagannath, Subramanian Dhandayuthapani   +3 more
doaj   +2 more sources

A Chymotrypsin-Dependent Live-Attenuated Influenza Vaccine Provides Protective Immunity against Homologous and Heterologous Viruses

Vaccines
Influenza virus is one of the main pathogens causing respiratory diseases in humans. Vaccines are the most effective ways to prevent viral diseases. However, the limited protective efficacy of current influenza vaccines highlights the importance of novel,
Peiqing He, Mengxuan Gui, Tian Chen, Yue Zeng, Congjie Chen, Zhen Lu, Ningshao Xia, Guosong Wang, Yixin Chen   +8 more
doaj   +2 more sources

Quality control procedure for Coccidial vaccines versus different routes of immunization [PDF]

Veterinary World, 2022
Background and Aim: Coccidiosis is an enteric infection caused by a protozoon (Eimeria tenella). Coccidiosis is known to have a negative impact on the economy. Coccidiosis is controlled using anticoccidial drugs, antibiotics, and vaccines.
Arwa Elnaggar, Hala Mahmoud, Sahar Saber
doaj   +1 more source