Results 71 to 80 of about 1,499,954 (350)

Research note: Comparison of live attenuated and non-attenuated Eimeria vaccines on safety following overdose administration using the European pharmacopoeia monograph model

Poultry Science
Live non-attenuated and attenuated coccidiosis vaccines are available and induce a solid immune response to Eimeria spp. However, knowledge regarding the safety of live non-attenuated Eimeria vaccines is still limited.
Marc Pagès, Andreu Albó, Gregori Bech-Sàbat, Roser Morató, Joan Molist-Badiola, Martina Dardi   +5 more
doaj   +1 more source

Current Advances in Zika Vaccine Development

Vaccines, 2022
Zika virus (ZIKV), an emerging arthropod-borne flavivirus, was first isolated in Uganda in 1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated with a dramatic burden worldwide. Since then, interventions to reduce the
Yuchen Wang, Lin Ling, Zilei Zhang, Alejandro Marin-Lopez   +3 more
doaj   +1 more source

Preventing the Next Pandemic: Is Live Vaccine Efficacious against Monkeypox, or Is There a Need for Killed Virus and mRNA Vaccines?

Vaccines, 2022
(1) Background: The monkeypox virus (MPV) is a double-stranded DNA virus belonging to the Poxviridae family, Chordopoxvirinae subfamily, and Orthopoxvirus genus.
A. Abdelaal, A. Reda, B. Lashin, B. Katamesh, A. Brakat, Balqees Al-Manaseer, Sayanika Kaur, Ankush Asija, Nimesh K. Patel, S. Basnyat, A. Rabaan, S. Alhumaid, Hawra Albayat, M. Aljeldah, B. A. Shammari, A. Al-Najjar, Ahmed K. Al-Jassem, Sultan T AlShurbaji, F. Alshahrani, Ahlam Alynbiawi, Zainab H. Alfaraj, Duaa H. Alfaraj, Ahmed H. Aldawood, Y. Sedhai, Victoria Mumbo, A. Rodríguez-Morales, R. Sah   +26 more
semanticscholar   +1 more source

Live attenuated intranasal influenza vaccine [PDF]

Human Vaccines & Immunotherapeutics, 2012
Annual vaccination is the most effective means of preventing and controlling influenza epidemics, and the traditional trivalent inactivated vaccine (TIV) is by far the most widely used. Unfortunately, it has a number of limitations, the most important of which is its poor immunogenicity in younger children and the elderly, the populations at greatest ...
S. Esposito, V. Montinaro, E. Groppali, R. Tenconi, M. Semino, N. Principi   +5 more
openaire   +5 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The Shigella Vaccines Pipeline

Vaccines, 2022
Shigella is the leading cause of global diarrheal deaths that currently lacks a licensed vaccine. Shigellosis drives antimicrobial resistance and leads to economic impact through linear growth faltering.
C. MacLennan, Stephanie Grow, Lyou-fu Ma, A. Steele   +3 more
semanticscholar   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Influenza Vaccination Strategies: Comparing Inactivated and Live Attenuated Influenza Vaccines

Vaccines, 2015
Influenza is a major respiratory pathogen causing annual outbreaks and occasional pandemics. Influenza vaccination is the major method of prophylaxis.
S. Sridhar, K. Brokstad, R. Cox
semanticscholar   +1 more source

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams, Malachi Keo, Jennifer Guo, Daire Daly, Richard Ahern, Kimon Zachary, Gregory Robbins, Rajesh T. Gandhi, Bragi Sveinsson, Adam de Havenon, Kevin N. Sheth, Otto Rapalino, Juan Eugenio Iglesias Gonzales, W. Taylor Kimberly, Shibani S. Mukerji   +14 more
wiley   +1 more source

Elegant and Innovative Recoding Strategies for Advancing Vaccine Development

Vaccines
Recoding strategies have emerged as a promising approach for developing safer and more effective vaccines by altering the genetic structure of microorganisms, such as viruses, without changing their proteins.
François Meurens, Fanny Renois, Uladzimir Karniychuk   +2 more
doaj   +1 more source