Results 231 to 240 of about 1,048,296 (327)

Integrating Affinity Chromatography in the Platform Process for Adenovirus Purification

Biotechnology and Bioengineering, EarlyView.
Peptide‐functionalized affinity resins with high adenovirus binding capacity, recovery, and contaminant removal afford excellent productivity, and reduced impurities in a three‐step purification process. ABSTRACT Adenoviral vectors (AdVs) are gaining prominence in cancer therapy and vaccine development, posing the need for a modern AdV manufacturing ...
Yuxuan Wu, Eduardo Barbieri, William K. Smith, Arianna Minzoni, Ryan E. Kilgore, Wenning Chu, Michael A. Daniele, Stefano Menegatti   +7 more
wiley   +1 more source

Vaccination for prevention of hearing loss: a scoping review. [PDF]

Commun Med (Lond)
Johri M, Téhinian S, Pérez Osorio MC, Barış E, Wahl B.   +4 more
europepmc   +1 more source

Pediatric Invasive Pneumococcal Disease in the United States in the Era of Pneumococcal Conjugate Vaccines

Clinical Microbiology Reviews, 2012
T. Tan
semanticscholar   +1 more source

N‐ to C‐Glycoside Rearrangement of Uridine 5′‐Phosphate in Two Enzymatic Steps for the Production of Pseudouridine 5′‐Phosphate

Biotechnology and Bioengineering, EarlyView.
The authors present a streamlined cascade reaction for one‐pot N‐C rearrangement of uridine‐5′‐phosphate (UMP) to pseudouridine‐5′‐phosphate (ΨMP; a key mRNA vaccine building block), in two enzymatic steps catalyzed by UMP nucleosidase (EC 3.2.2.10) and ΨMP C‐glycosidase (EC 4.2.1.70).
Martin Pfeiffer, Franziska Guld, Bernd Nidetzky   +2 more
wiley   +1 more source

Indirect Comparison of PCV20 Immunogenicity with PCV10 in Pediatric 3 + 1 and 2 + 1 Schedules. [PDF]

Infect Dis Ther
Dunne EM, Struwig VA, Lowe W, Wilson CH, Perdrizet JE, Tamimi N, Hayford K, Jodar L, Gessner BD, Theilacker C.   +9 more
europepmc   +1 more source

The contribution of extracellular RNA and its derived biomaterials in disease management

BMEMat, EarlyView.
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei, Zhangyi Wang, Zixuan Qin, Qianqian Wan, Yutao Li, Franklin R. Tay, Chenyu Wang, Tong Zhang, Lina Niu   +8 more
wiley   +1 more source

Immunogenicity and Safety of the Higher-Valent Pneumococcal Conjugate Vaccine vs the 13-Valent Pneumococcal Conjugate Vaccine in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials. [PDF]

Open Forum Infect Dis
Ngamprasertchai T, Ruenroengbun N, Kajeekul R.   +2 more
europepmc   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Designing next‐generation immune cell therapies with nanomaterials

BMEMat, EarlyView.
Nanomaterials are transforming immune cellular therapies (ICT) by addressing challenges like tumor accessibility and lengthy manufacturing. This perspective highlights innovations such as magnetic nanoparticles for target identification, lipid nanoparticles for T cell stimulation, and nanoparticle‐mediated gene cytokine delivery. These advances promise
Kangfu Chen, Wenhan Wang, Zongjie Wang
wiley   +1 more source

Vaccinations in Pediatric Hematology and Oncology: Biologic Basis, Clinical Applications, and Perspectives. [PDF]

Vaccines (Basel)
Martire B, Beni A, Mastrototaro MF, Santilli V, Ottaviano G, Montin D, Rizzo C, Sgrulletti M, Miraglia Del Giudice M, Costagliola G, Moschese V, Italian Society of Pediatric Allergology and Immunology (SIAIP) Vaccine Committee.   +11 more
europepmc   +1 more source