Five-Year Immune Persistence of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW-TT) and Immunogenicity and Safety of a Booster Dose in Children. [PDF]
Martinón-Torres F+7 more
europepmc +1 more source
Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies
Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang+8 more
wiley +1 more source
The Current Status in Terms of Vaccination for Individuals Infected with Human Immunodeficiency Virus. [PDF]
Xu N, Shen Y, Huang W, Nie J.
europepmc +1 more source
Objective: Cancer remains a global health challenge, necessitating new therapeutic options. Phytochemicals, with diverse chemical structures and biological activities, show promise as anticancer agents. This review explores key phytochemicals, their mechanisms, and their potential integration into cancer therapy.
Alaa A. A. Aljabali+11 more
wiley +1 more source
Vaccination Coverage in Hematopoietic Stem Cell Transplant Patients. [PDF]
Bouzas-Rodríguez A+4 more
europepmc +1 more source
Promising Prodiginins Biological Activities
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto+6 more
wiley +1 more source
PCV13-Serotype Breakthrough Pneumococcal Disease in Infants Receiving High-Valency Conjugate Vaccines: Population-Level Modeling in France. [PDF]
Bakker KM+7 more
europepmc +1 more source
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves+3 more
wiley +1 more source
A Narrative Review of Pneumococcal Conjugate Vaccine Choices for Greater Access and Protection against Pneumococcal Diseases in the Philippines. [PDF]
Lota MMM+6 more
europepmc +1 more source
A series of 2‐substituted adenosine 5′‐O‐triphosphate derivatives is synthesized and tested as substrates for polymerases. In vitro transcription with T7 RNA polymerase, primer extension with engineered DNA polymerases, or 3′‐labelling with poly(A) polymerase are used for enzymatic synthesis of base‐modified RNA.
Ugnė Šinkevičiūtė+5 more
wiley +1 more source