Results 41 to 50 of about 73,005 (301)

Progress towards meningitis prevention in the conjugate vaccines era

open access: yesBrazilian Journal of Infectious Diseases
Acute bacterial meningitis is an important cause of morbidity and mortality among children less than five years old. Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis are the most important agents of bacterial meningitis in ...
Cristina Aparecida Borges Laval   +4 more
doaj   +1 more source

How the Knowledge of Interactions between Meningococcus and the Human Immune System Has Been Used to Prepare Effective Neisseria meningitidis Vaccines

open access: yesJournal of Immunology Research, 2015
In the last decades, tremendous advancement in dissecting the mechanisms of pathogenicity of Neisseria meningitidis at a molecular level has been achieved, exploiting converging approaches of different disciplines, ranging from pathology to microbiology,
R. Gasparini   +7 more
doaj   +1 more source

Herd Protection against Meningococcal Disease through Vaccination

open access: yesMicroorganisms, 2020
Reduction in the transmission of Neisseria meningitidis within a population results in fewer invasive disease cases. Vaccination with meningococcal vaccines composed of high weight capsular polysaccharide without carrier proteins has minimal effect ...
Stephen A. Clark, Ray Borrow
doaj   +1 more source

Development of a novel glycoengineering platform for the rapid production of conjugate vaccines

open access: yesMicrobial Cell Factories, 2023
Conjugate vaccines produced either by chemical or biologically conjugation have been demonstrated to be safe and efficacious in protection against several deadly bacterial diseases.
Sherif Abouelhadid   +15 more
doaj   +1 more source

The Hajj 2019 Vaccine Requirements and Possible New Challenges [PDF]

open access: yes, 2019
Each year millions of pilgrims perform the annual Hajj from more than 180 countries around the world. This is one of the largest mass gathering events and may result in the occurrence and spread of infectious diseases.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

Pneumococcal serotypes in children in 4 European countries [PDF]

open access: yes, 2010
After heptavalent pneumococcal conjugate vaccine (PCV7) was marketed in France, Spain, Belgium, and England and Wales (United Kingdom), invasive disease from non-PCV7 serotypes (NVT) increased. Adjusted serotype-specific incidences among children
Fenoll, Asuncion   +8 more
core   +3 more sources

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

open access: yesAdvanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Recent Advances in Toll Like Receptor-Targeting Glycoconjugate Vaccines

open access: yesMolecules, 2018
Many malignant cell surface carbohydrates resulting from abnormal glycosylation patterns of certain diseases can serve as antigens for the development of vaccines against these diseases.
Qingjiang Li, Zhongwu Guo
doaj   +1 more source

Recommended immunization schedule for children and adolescents: Immunization Guideline (8th edition) released by the Korean Pediatric Society in 2015 [PDF]

open access: yesKorean Journal of Pediatrics, 2016
This report includes the recommended immunization schedule table for children and adolescents based on the 8th (2015) and revised 7th (2012) Immunization Guidelines released by the Committee on Infectious Diseases of the Korean Pediatric Society (KPS ...
Jong-Hyun Kim   +11 more
doaj   +1 more source

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