Results 181 to 190 of about 80,375 (245)

Inactivated Enterovirus 71 Particle Aggregation Stability: Dynamic Light Scattering Analysis and Stabilizer Identification. [PDF]

Vaccines (Basel)
Yang A, Yang D, Pang D, Yang J, Wang W, Du Y, Wan X, Meng S, Guo J, Shen S.   +9 more
europepmc   +1 more source

Tumor‐Infiltrating Nociceptor Neurons in Ovarian Cancer Treatment Resistance

Advanced Biology, Volume 10, Issue 3, March 2026.
This study shows that high‐grade serous ovarian carcinomas (HGSOC) are significantly more innervated than the other histological subtypes. HGSOC small extracellular vesicles (sEVs) promote neurite outgrowth in vitro. Analysis of pre‐ and post‐treatment HGSOC samples shows that innervation increases post‐chemotherapy.
Allison Jorgensen, Daniel W. Vermeer, Euihye Jung, Caitlin S. Williamson, Dalia K. Omran, Lauren E. Schwartz, Ju‐Yoon Yoon, Jeffrey Barr, Ashley L. Tetlow, Camille V. Trinidad, Ronny Drapkin, Andrew K. Godwin, Paola D. Vermeer   +12 more
wiley   +1 more source

Engineered VP1 mRNA Vaccine Induces Immunity and Complete Protection Against Feline Calicivirus in Cats. [PDF]

Transbound Emerg Dis
Zhang MD, Xie ZF, Li XH, Huang W, Qian QY, Cao HT, Liu JW, Zhang YQ, Wang B, Qin Y, Shi FS, Tang JB, Huang YW, Yang YL.   +13 more
europepmc   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

The impact of innate and humoral immune mechanisms on vaccine induced protection against avian influenza H9N2 in broilers. [PDF]

Sci Rep
Asaad HM, Hassanin O, Saif-Edin M, Ibrahim RS, Mohamed MA, Hamad M, Abdullatif TM.   +6 more
europepmc   +1 more source

A High Throughput Microfluidic Approach for the Continuous Manufacture of Ibuprofen Nanocrystals

Advanced Materials Technologies, Volume 11, Issue 5, 6 March 2026.
A robust, continuous manufacturing platform using a high‐throughput microfluidic reactor addresses key scalability challenges in pharmaceutical production. This process efficiently generates crystalline ibuprofen nanoparticles with superior control over size and distribution.
Shorooq Abukhamees, Maximilian Besenhard, Rawan Fitaihi, Hei Ming Kenneth Ho, Asterios Gavriilidis, Duncan Q. M. Craig   +5 more
wiley   +1 more source

Comparison of safety and immunogenicity between Healive®, Havrix® and live attenuated Hepatitis A vaccines in pediatric population: a systematic review with meta-analysis. [PDF]

Ital J Pediatr
Abo Zeid M, Elrosasy A, Farho MA, Rifai M, Aboelkhier MM, Elkhrashy MN, Zabady AH, Zaki MSA, Hamed EM, Dawood SA, Abuzaid Y.   +10 more
europepmc   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Innate Immunity Trained in the Protective Response of Vaccine Candidates Against Intracellular Pathogens. [PDF]

Vaccines (Basel)
Oliveira JBS, Silva LA, Sousa MFS, Junior AMF, Almeida CG, Barducci RS, Milazzotto MP, Brandão HM, Santos RL, Paixão TA.   +9 more
europepmc   +1 more source