Results 171 to 180 of about 1,302,625 (339)

Artificial Intelligence‐Driven Nanoarchitectonics for Smart Targeted Drug Delivery

open access: yesAdvanced Materials, EarlyView.
This perspective introduces an artificial intelligence (AI)‐driven nanoarchitectonics framework for targeted drug delivery, combining database‐guided nanocarrier design, machine learning (ML)‐assisted surface engineering with a designed targeting system, and in silico modeling for dynamic optimization.
Hayeon Bae   +6 more
wiley   +1 more source

How Real‐Time Kinetics Explain the Different Interaction of Cubosomes and Hexosomes Nanoparticles with Lipid Membranes

open access: yesAdvanced Materials Interfaces, EarlyView.
GMO cubosomes and DOPE hexosomes interact differently with lipid membranes: cubosomes exchange lipid molecules with the membranes, destabilizing them when the membranes do not contain cholesterol. Hexosomes interact more gently with membranes and tend to fuse and incorporate into them.
Mario Campana   +4 more
wiley   +1 more source

Disinfectant Action of Phenol and of Alcohol in T.A.B.C. Vaccine [PDF]

open access: green, 1942
J. C. Cruickshank   +3 more
openalex   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao   +6 more
wiley   +1 more source

A Hydrophilic Hollow Microneedle Platform for Sampling Interstitial Fluid and On‐Site Biomarker Detection

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents a superhydrophilic 3D‐printed hollow microneedle patch for continuous interstitial fluid (ISF) extraction and on‐patch biomarker sensing. Combining projection micro‐stereolithography and chemical vapor deposition, high‐resolution microneedles with enhanced wettability are fabricated, enabling passive ISF uptake without external ...
Taher Abbasiasl   +7 more
wiley   +1 more source

Long-Term Impacts of Invasive Meningococcal Disease on Survivors and Their Caregivers in the United States and Canada

open access: yesInfectious Diseases and Therapy
Introduction Adolescents and young adults are among those most often impacted by invasive meningococcal disease (IMD), and survivors are often left with serious and permanent physical, neurological, psychological, or systemic complications.
Todd Wolynn   +12 more
doaj   +1 more source

Multitasking Smart Intestinal Capsule Robot: A Cutting‐Edge Platform for Sampling, Diagnosis, and Therapy

open access: yesAdvanced Robotics Research, EarlyView.
Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen   +3 more
wiley   +1 more source

SPA14 liposomes combining saponin with fully synthetic TLR4 agonist provide adjuvanticity to hCMV vaccine candidate

open access: yesnpj Vaccines
In the aim of designing and developing a novel saponin-based adjuvant system, we combined the QS21 saponin with low microgram amounts of the fully synthetic TLR4 agonist, E6020, in cholesterol-containing liposomes.
Ernesto Luna   +13 more
doaj   +1 more source

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