Results 261 to 270 of about 1,792,624 (390)

Ionizable lipid nanoparticles of mRNA vaccines elicit NF-κB and IRF responses through toll-like receptor 4 [PDF]

Amanda E Zelkoski, Zhongyan Lu, Gauthaman Sukumar, Clifton L. Dalgard, Hooda Said, Mohamad‐Gabriel Alameh, Edward Mitre, Allison M. W. Malloy   +7 more
openalex   +1 more source

Vaccines and vaccination

, 2010
John D. Grabenstein, Walter L. Straus, Mark B. Feinberg   +2 more
openaire   +1 more source

In Situ Engineering of Tumor Cells as Self‐Sustaining cDC1 Programming Factories for Effective Cancer Immunotherapy

Advanced Science, EarlyView.
The fused EV platform AS16‐EL@MPLA/p‐FX reprograms tumor cells into cytokine‐producing factories that continuously secrete XCL1 and FLT3L to recruit and differentiate cDC1s, while embedded MPLA activates them through TLR4 signaling and AS16 prevents their exhaustion, thereby enhancing antitumor immunity and establishing durable immune memory against ...
Shuiling Jin, Xiaoxi Wang, Bingyu Li, Xueqin Zhu, Zimai Liu, Jiao Lu, Yuanyuan Wei, Zixian Wu, Kai Li, Tiantian Zhang, Zonghong He, Pingping Zhu, Yuanming Qi, Benyu Liu, Hui Liu, Yongchao Wang, Zhenzhen Chen   +16 more
wiley   +1 more source

Brief Comparison of Novel Influenza Vaccine Design Strategies. [PDF]

Vaccines (Basel)
Chai S, Ye C, Fan C, Jiang H.
europepmc   +1 more source

Broad protection against clade 1 sarbecoviruses after a single immunization with cocktail spike-protein-nanoparticle vaccine [PDF]

Peter Halfmann, Kathryn Loeffler, Augustine Duffy, Makoto Kuroda, Jie Yang, Elizabeth Wright, Yoshihiro Kawaoka, Ravi S. Kane   +7 more
openalex   +1 more source

Nanoparticle‐Modified Nanofibers Induce Ferroptosis and Stimulate Antitumor Immunity for Melanoma Therapy

Advanced Science, EarlyView.
This study presents a nanoparticle‐embedded nanofiber (5F/STFM/R‐ES) to inhibit melanoma growth and reduce the risk of metastasis and recurrence. The drug delivery system induces ferroptosis and potentiates immunotherapy through resiquimod (R848) and Fe/Mn‐based metal‐polyphenol networks (TFM).
Mingyang Li, Rongrong Li, Baotong Xu, Yuhan Lian, Chenyu Yang, Jingwen Li, Junhao Liang, Linhan Ding, Dongsheng Zhang, Jing Guo, Xiao Fu   +10 more
wiley   +1 more source

Cancer vaccines: advances, hurdles, and future directions. [PDF]

Explor Target Antitumor Ther
Vlachostergios PJ.
europepmc   +1 more source

An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions

, 2008
Joseph G. Joyce, Isaac J. Krauss, Hong Chang Song, David Opalka, Karen M. Grimm, Deborah D. Nahas, Mark T. Esser, Renee Hrin, Meizhen Feng, Vadim Dudkin, Michael Chastain, John W. Shiver, Samuel J. Danishefsky   +12 more
openalex   +1 more source

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

Advanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang, Youtao Wang, Cong Sun, Tao Liu, Zengfeng Wu, Lipeng Chen, Lina Chen, Penglin Li, Zhengkang Li, Cangui Zhang, Bingyun Lu, Ye Chen, Bing Gu, Qian Zhong, Xin Wei Wang, Mu‐Sheng Zeng, Jinping Liu   +16 more
wiley   +1 more source

Advances in Cancer Vaccines for Digestive System Cancers: A Systematic Analysis of Clinical Trials. [PDF]

Cancer Manag Res
Li J, Wang P.
europepmc   +1 more source