Results 261 to 270 of about 1,772,507 (392)

ADAR1 as a Placental Innate Immune Rheostat Sustaining the Homeostatic Balance of Intrinsic Interferon Response at the Maternal‐Fetal Interface

Advanced Science, EarlyView.
This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen, Xiangchao Xu, Jiahao Chen, Huiru Zhang, Wanshan Zheng, Wenzhe Yu, Xiaoqian Hu, Bin Cao   +7 more
wiley   +1 more source

Strategies and challenges for immunisation of children under 5 years in primary health care in different countries: a scoping review. [PDF]

BMC Public Health
Freitas CAM, Vilasbôas ALQ, de Brito Lima Prado NM.   +2 more
europepmc   +1 more source

THE TREATMENT OF GONOCOCCUS INFECTIONS BY VACCINES. [PDF]

, 1909
JohnW.H. Eyre, B. Stewart
openalex   +1 more source

Securing poultry production from the ever-present Eimeria challenge [PDF]

, 2013
Blake, D P, Tomley, F M
core   +2 more sources

Vaccine and Vaccination

American Journal of Public Health and the Nations Health, 1930
openaire   +3 more sources

METTL10‐Mediated PIAS3 Methylation Links Purine Metabolism to Gastric Cancer Progression

Advanced Science, EarlyView.
METTL10‐mediated methylation of PIAS3 at K442 inhibits its SUMO E3 ligase activity toward MITF. This reduces MITF SUMOylation and subsequent RNF4‐mediated ubiquitination, leading to MITF protein accumulation and gastric cancer progression. Abstract Metabolic dysregulation plays a significant role in the development of gastric cancer (GC).
Jinshui Tan, Huiwen Zhou, Jingsong Ma, Chensong Zhang, Yuhua Tan, Baoding Zhang, Jiabao Zhao, Ao Cheng, Chengyu Yang, Meijuan Xu, Shengyi Zhou, Yubo Xiong, Zeyang Lin, Guangchao Pan, Wenjie Ye, Mengya Zhong, Yang Yang, Yifan Zhuang, Shao‐Wei Li, Xianming Deng, Xuehui Hong   +20 more
wiley   +1 more source

Emerging strategies for monkeypox: antigen and antibody applications in diagnostics, vaccines, and treatments. [PDF]

Mil Med Res
Wang W, Li JX, Long SQ, Liu ZN, Li XP, Peng ZH, Zheng JD, Liao YH.   +7 more
europepmc   +1 more source

Beef-Heart Charcoal Agar for the Preparation of Pertussis Vaccines [PDF]

, 1953
Lucy Mishulow, Leslie S. Sharpe, Lillian L. Cohen   +2 more
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Physicians' knowledge of, and willingness to encourage caregivers to partake in the RTS S/AS01 and R21 matrix M malaria vaccines roll out - a national survey in Nigeria. [PDF]

BMC Infect Dis
Oboh MA, Adeleke OT, Adeleke OV, Awotunde TA.   +3 more
europepmc   +1 more source