Results 271 to 280 of about 1,792,624 (390)

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, EarlyView.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source

A Phase 3 study to assess the safety and immunogenicity of a quadrivalent meningococcal conjugate vaccine (MenACYW-TT) co-administered with routine pediatric vaccines in healthy infants in the USA and Puerto Rico. [PDF]

Hum Vaccin Immunother
Campbell JD, Gupta S, Dhingra MS, Zambrano B, Gan L, B'Chir S, Chaix J, Syrkina O, Masson J, Liabis O, Rehm C.   +10 more
europepmc   +1 more source

Application of carbon nanotubes in cancer vaccines: Achievements, challenges and chances

, 2019
Hatem A. F. M. Hassan, Sandra S. Diebold, Lesley A. Smyth, Adam A. Walters, Giovanna Lombardi, Khuloud T. Al‐Jamal   +5 more
openalex   +2 more sources

Eradicating infectious disease using weakly transmissible vaccines [PDF]

, 2016
Scott L. Nuismer, Benjamin M. Althouse, Ryan May, James J. Bull, Sean P. Stromberg, Rustom Antia   +5 more
openalex   +1 more source

Vaccines [PDF]

Clinical Therapeutics, 2017
openaire   +2 more sources

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, EarlyView.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

A review of vaccinology and <i>ex vivo</i> antigen-loaded dendritic cells: A different approach to infectious disease vaccines. [PDF]

Hum Vaccin Immunother
Dillman RO, Nistor GI, Keirstead HS.
europepmc   +1 more source

Edible Pneumatic Battery for Sustained and Repeated Robot Actuation

Advanced Science, EarlyView.
This work presents an edible energy source and valve system to power soft, pneumatically driven edible robots. A chemical reaction between sodium bicarbonate and citric acid generates carbon dioxide gas, and a pressure‐triggered edible valve enables self‐repetitive motion of the edible actuator.
Bokeon Kwak, Shuhang Zhang, Alexander Keller, Qiukai Qi, Jonathan Rossiter, Dario Floreano   +5 more
wiley   +1 more source

Publisher Correction: Modeling gonorrhea vaccination to find optimal targeting strategies that balance impact with cost-effectiveness. [PDF]

NPJ Vaccines
Leng T, Whittles LK, Nikitin D, White PJ.   +3 more
europepmc   +1 more source

MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-ASSOCIATED VACCINE PROTECTION FROM SIMIAN IMMUNODEFICIENCY VIRUS-INFECTED PERIPHERAL-BLOOD CELLS [PDF]

, 1994
Boes, J, Bontrop, RE, Cranage, M, de Vries, P, Dings, M, Dubbes, R, Heeney, JL, Jonker, M, Koornstra, W, Niphuis, H, Norley, S, Osterhaus, A, Otting, N, ten Haaft, P, van Els, C   +14 more
core   +1 more source