Results 31 to 40 of about 308,174 (247)

Vaccines

, 2019
The dataset (Vaccines) contains background subtracted frequencies of CD4 and CD8 T cells producing a combination of IFNγ, IL-2, TNF and IL-17 in response to stimulation by vaccine-specific antigens for the vaccines included in the paper "A head-to-head ...
Miguel Julio Rodo (5561078), Elisa Nemes (295125), Francesca Little (5796548), Thomas Scriba (5793185), Virginie Rozot (5793212), One B. Dintwe (4900906), Mark Hatherill (23097)   +6 more
core   +1 more source

Porcine Circovirus Type 2 Vaccines: Commercial Application and Research Advances

, 2022
Porcine circovirus type 2 (PCV2) infection can lead to porcine circovirus-associated disease (PCVAD), causing great economic losses to the global swine industry.
Guo, Jinshuo, Jue Liu, Zhou, Jianwei, Liu, Jue, Hou, Lei, Dedong Wang, Yongqiu Cui, Xufei Feng, Lei Hou, Jinshuo Guo, Jianwei Zhou, Cui, Yongqiu, Wang, Dedong, Feng, Xufei   +13 more
core   +1 more source

Enhanced Systemic Humoral Immune Response Induced in Mice by Generalized Modules for Membrane Antigens (GMMA) Is Associated with Affinity Maturation and Isotype Switching

Vaccines, 2023
Generalized Modules for Membrane Antigens (GMMA) are outer membrane vesicles derived from Gram-negative bacteria that can be used to design affordable subunit vaccines. GMMA have been observed to induce a potent humoral immune response in preclinical and
Diego Piccioli, Francesca Buricchi, Marta Bacconi, Nicoletta Bechi, Barbara Galli, Francesca Ferlicca, Enrico Luzzi, Elena Cartocci, Sara Marchi, Giacomo Romagnoli, Renzo Alfini, Roberta Di Benedetto, Simona Gallorini, Silvana Savino, Brunella Brunelli, Erika Bartolini, Francesca Micoli   +16 more
doaj   +1 more source

Improving cellular cancer vaccines [PDF]

, 2010
Immunization with cancer cells is of great demand in anti-cancer therapy. However, current cellular vaccines are inefficient and there are questions regarding their overall safety. We report a simple and straightforward approach for improving of cellular
Petr Lokhov
core  

Review of meningococcal vaccines with updates on immunization in adults [PDF]

, 2014
Meningococcal disease is a serious and global life-threatening disease. Six serogroups (A, B, C, W-135, X, and Y) account for the majority of meningococcal disease worldwide.
Dbaibo, Ghassan S., Ghanem, Soha T., Zahlanie, Yorgo C., Hammadi, Moza M., Dbaibo G.S., Zahlanie Y.C., Hammadi M.M., Ghanem S.T.   +7 more
core   +1 more source

HBV Vaccines: Advances and Development

, 2023
Hepatitis B virus (HBV) infection is a global public health problem that is closely related to liver cirrhosis and hepatocellular carcinoma (HCC). The prevalence of acute and chronic HBV infection, liver cirrhosis, and HCC has significantly decreased as ...
Ruixian Xu, Jun Xu, Faisal Mahmood, Jinyang Zhang, Xueshan Xia, Maher Un Nisa Awan, Yuzhu Song, Jia Wei, Juan Peng, Qinqin Han   +9 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A phase I, randomized, controlled, dose-ranging study of investigational acellular pertussis (aP) and reduced tetanus-diphtheria-acellular pertussis (TdaP) booster vaccines in adults

Human Vaccines & Immunotherapeutics, 2018
Despite high vaccination coverage worldwide, pertussis has re-emerged in many countries. This randomized, controlled, observer-blind phase I study and extension study in Belgium (March 2012–June 2015) assessed safety and immunogenicity of investigational
Geert Leroux-Roels, Maria Lattanzi, Claudia Dovali Solis, Mario Contorni, Marco Costantini, Luca Moraschini, Monia Bardelli, Sylvie Bertholet, Erica Borgogni, Francesca Buricchi, Rocco Cantisani, Elisa Faenzi, Oretta Finco, Rosanna Leuzzi, Mariagrazia Pizza, Domenico Rosa, Francesca Schiavetti, Anja Seubert, Fabiana Spensieri, Gianfranco Volpini, Luisanna Zedda, Giuseppe Del Giudice, Ilaria Galgani   +22 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The development of contraceptive vaccines [PDF]

, 2002
The use of vaccination as a means of controlling fertility was established during the last decade with the publication of a successful Phase II trial demonstrating the efficacy of this approach to family planning.
Delves, PJ
core