Results 121 to 130 of about 96,968 (259)

Reemergence of Vaccinia Virus during Zoonotic Outbreak, Pará State, Brazil

open access: yesEmerging Infectious Diseases, 2013
In 2010, vaccinia virus caused an outbreak of bovine vaccinia that affected dairy cattle and rural workers in Pará State, Brazil. Genetic analyses identified the virus as distinct from BeAn58058 vaccinia virus (identified in 1960s) and from smallpox ...
Felipe L. de Assis   +9 more
doaj   +1 more source

Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]

open access: yes, 2011
Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle   +3 more
core   +2 more sources

Recombinant chimeric horsepox virus (TNX-801) is attenuated relative to vaccinia virus strains in both in vitro and in vivo models

open access: yesmSphere
Recombinant chimeric horsepox virus (TNX-801) is a preclinical vaccine in development against mpox and smallpox. In this report, we investigated the potential phenotypic differences in in vitro and in vivo models between TNX-801 and older vaccinia virus (
Stephanie V. Trefry   +17 more
doaj   +1 more source

Protection of Mice Against the Vaccinia Virus by the Administration of Phenoxythiouracils [PDF]

open access: bronze, 1951
R. L. Thompson   +4 more
openalex   +1 more source

Assessing recombinant vaccinia virus as a delivery system for fertility control vaccines in the brushtail possum (Trichosurus vulpecula)

open access: yesJulius-Kühn-Archiv, 2011
The introduced brushtail possum (Trichosurus vulpecula) is a major threat to native biodiversity and agricultural production in New Zealand. Research on non-lethal management methods is focussed on fertility control, and aims to develop zona pellucida ...
Duckworth, J.   +7 more
doaj   +1 more source

Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors. [PDF]

open access: yes, 2009
Protein kinase PKR (also known as EIF2AK2) is activated during viral infection and phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF2), leading to inhibition of translation and viral replication. We report fast evolution
Dever, Thomas E   +4 more
core  

THE RELATIONSHIP OF VARIOLA AND VACCINIA [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1913
The relationship of variola and vaccinia has been discussed since Jenner's day, but no satisfactory explanation found. Yet there is an explanation so simple, complete and satisfactory that as thorough an investigation of the literature as I have been able to make in Manila in three months does not reveal any evidence in opposition, and does yield an ...
openaire   +2 more sources

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