Results 101 to 110 of about 63,132 (220)
A Global Perspective of Childhood Vaccinations: Past, Present, and Future—From Smallpox to mRNA
Acta Paediatrica, Volume 115, Issue 11, Page 2498-2504, November 2026.ABSTRACT Childhood immunisation is one of the most successful public health interventions in history, preventing millions of deaths and substantially reducing global child mortality. This mini‐review summarises the historical development of childhood vaccines, the role of global coordination in expanding immunisation coverage, and the innovations that ...
Tobias Alfvén, Tania Reza, Alieu Sowe
wiley +1 more source
Optimizing Microneutralization and IFN-γ ELISPOT Assays to Evaluate Mpox Immunity
VaccinesBackground: Available assays to measure pox virus neutralizing antibody titers are laborious and take up to 5 days. In addition, assays to measure T cell responses require the use of specific antigens, which may not be the same for all pox viruses.
Yinyi Yu +7 more
doaj +1 more source
Vaccinia virus expressing ICP47 : a novel platform for cancer vaccines highlighting tumor epitopes and hiding viral antigens [PDF]
, 2010 Background Recombinant poxviruses expressing tumor associated antigens (TAAs) are evaluated since 20 years as immunogenic vaccine vector in clinical trials.
Raafat, Nermin Abdel Fattah
core +1 more source
Trained Immunity in Childhood Vaccination
Acta Paediatrica, Volume 115, Issue 11, Page 2402-2413, November 2026.Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai +2 more
wiley +1 more source
Viruses, 2010 Hexadecyloxypropyl-cidofovir (HDP-CDV) is a novel ether lipid conjugate of (S)-1-(3-hydroxy-2-phosphonoylmethoxypropyl)-cytosine (CDV) which exhibits a remarkable increase in antiviral activity against orthopoxviruses compared with CDV.
Karl Y. Hostetler
doaj +1 more source
Exploring the Development of Vaccine Platforms, With a Particular Focus on the COVID‐19 Pandemic
Acta Paediatrica, Volume 115, Issue 11, Page 2421-2426, November 2026.ABSTRACT Vaccines have been a cornerstone of human health for more than 200 years and one of the most important tools to reduce childhood deaths caused by pathogens. The concept of vaccines is basically to take something safe, make it immunogenic and induce an immune response in the host that will protect it against something dangerous. Live attenuated
Matti Sällberg
wiley +1 more source
Group 2 Vaccinia Virus, Brazil
, 2012 In 2011, vaccinia virus caused an outbreak of bovine vaccinia, affecting dairy cattle and dairy workers in Brazil. Genetic and phenotypic analyses identified this isolate as distinct from others recently identified, thereby reinforcing the hypothesis ...
Cláudio Antônio Bonjardim +9 more
core +1 more source
VRK2 (vaccinia related kinase 2) [PDF]
, 2012 Review on VRK2 (vaccinia related kinase 2), with data on DNA, on the protein encoded, and where the gene is ...
Vázquez-Cedeira, Marta +9 more
core +1 more source
Induction of cytolytic T lymphocytes directed towards the V3 loop of the human immunodeficiency virus type 1 external glycoprotein gp120 by p55gag/V3 chimeric vaccinia viruses [PDF]
, 1993 T cell-mediated cytotoxicity may play an important role in controlling infection by human immunodeficiency virus (HIV). In order to study the ability of rationally designed antigens to induce cytolytic T lymphocytes (CTLs) we replaced stretches of 30 to ...
Deml, Ludwig +4 more
core +1 more source