Results 91 to 100 of about 57,005 (244)

Progressive vaccinia acquired through zoonotic transmission in a patient with HIV/AIDS, Colombia

, 2020
In March 2015, a patient in Colombia with HIV/AIDS was hospitalized for disseminated ulcers after milking cows that had vesicular lesions on their udders.
Patel, Nishi, Li, Yu, Mauldin, Matthew R., Páez Martínez, Andrés, Pinzón Nariño, Nicole, Benjumea Nieto, Paula, Torres-Castellanos, Diego, Ávila-Robayo, Paola, Gracia Romero, Martha, Satheshkumar, Panayampalli Subbian, Usme Ciro, José Aldemar, Wilkins, Kimberly, Petersen, Brett W., Páez-Martinez, Andrés, Giraldo, Ivan, Usme-Ciro, José A., Styczynski, Ashley, Davidson, Whitni, Gracia-Romero, Martha, Burgado, Jillybeth, Pinzón-Nariño, Nicole, Torres Castellanos, Diego, Benjumea-Nieto, Paula, Satheshkumar, Panayampalli S., Laiton Donato, Katherine, Nakazawa, Yoshinori, Avila Robayo, Paola, Laiton-Donato, Katherine   +27 more
core   +1 more source

Severe Scrotal Cellulitis in a Young Man

JEADV Clinical Practice, EarlyView.
Hamad El Hajj, Vera Al Baaklini, Dima Jeha, Alfred Ammoury   +3 more
wiley   +1 more source

Combined MEK1/2 and Autophagy Inhibition Suppresses Tumor Growth via STING‐Mediated Type I Interferon Response in iCCA

Cancer Science, EarlyView.
Through bioinformatic analyses, iCCA cell models, and in vivo xenograft experiments, we show that autophagy inhibition sensitizes iCCA to MEK1/2 blockade by enhancing STING‐dependent type I interferon signaling. These findings support combined MEK1/2 and autophagy inhibition as a promising therapeutic strategy for iCCA. ABSTRACT The RAF–MEK–ERK pathway
Chengqiang Sun, Zheng Gao, Enfu Dong, Liangxia Ding, Shanru Feng, Jiafeng Chen, Pascal Kwangwari, Yinghong Shi, Weiren Liu, Xin Zhang, Ao Huang, Jian Zhou, Sheng Wang, Jia Fan, Xiutao Fu, ZhenBin Ding   +15 more
wiley   +1 more source

STUDIES IN VACCINIA. [PDF]

The Lancet, 1922
n ...
openaire   +1 more source

HIV‐1 viral load and reservoir size remain stable following SARS‐CoV‐2 mRNA vaccination in people with HIV

HIV Medicine, EarlyView.
Abstract Background The potent immunogenicity of mRNA vaccination raised concerns about its impact on HIV‐1 viral load (VL) and reservoir size in people with HIV, which could drive vaccine hesitancy. As part of a prospective clinical trial, we investigated whether SARS‐CoV‐2 mRNA vaccination induced changes in VL and reservoir size after a 1‐year three‐
Oscar Kieri, Bianca B Jütte, Jan Vesterbacka, Soo Aleman, Hans‐Gustaf Ljunggren, Marcus Buggert, J Peter Svensson, Anders Sönnerborg, Piotr Nowak   +8 more
wiley   +1 more source

A Pseudovirus Nanoparticle Displaying the Vaccinia Virus L1 Protein Elicited High Neutralizing Antibody Titers and Provided Complete Protection to Mice against Mortality Caused by a Vaccinia Virus Challenge

Vaccines
The recent worldwide incidence of mpox infection and concerns about future emerging variants of mpox viruses highlight the need for the development of a new generation of mpox vaccines.
Pengwei Huang, Ming Xia, Frank S. Vago, Wen Jiang, Ming Tan   +4 more
doaj   +1 more source

Modification of H-2 Antigenic Sites by Enzymatic Treatment Influences Virus-Specific Target Cell Lysis [PDF]

, 1976
Vaccinia virus-infected cells were treated enzymatically to remove H-2 antigenic sites. The effect of this procedure on virus-specific cell-mediated cytolysis (CMC) and virus-specific antibody-mediated cytolysis (AMC) was tested. Due to the inhibition of
Ertl, H C, Koszinowski, Ulrich H., Koszinowski, U H, Ertl, H.   +3 more
core  

Salt Treatment Confers Protection Against Acute Carp Edema Virus Reinfection While Promoting Viral Persistence

Journal of Fish Diseases, EarlyView.
ABSTRACT Carp edema virus (CEV) infects the common carp (Cyprinus carpio) and causes the lethal koi sleepy disease (KSD). Signs of KSD include respiratory, detoxification, and osmoregulatory difficulties. Salt treatment re‐equilibrates blood sodium levels and can save the fish. However, it is unclear whether these fish are immunized, remain chronically
Mikolaj Adamek, Maria Zawisza, Justin Tze Ho Chan, Alexander Rebl, Felix Teitge, Alberto Falco, Anne‐Carina Miebach, Verena Jung‐Schroers, Esteban Soto, Jiří Kyslík, Dieter Steinhagen, Krzysztof Rakus, Tomas Korytar   +12 more
wiley   +1 more source

Should Remaining Stockpiles of Smallpox Virus (Variola) Be Destroyed?

Emerging Infectious Diseases, 2011
In 2011, the World Health Organization will recommend the fate of existing smallpox stockpiles, but circumstances have changed since the complete destruction of these cultures was first proposed.
Raymond S. Weinstein
doaj   +1 more source

A Recombinant Vaccinia Virus Encoding the Interferon-Inducible T-Cell Alpha Chemoattractant is Attenuated In Vivo

, 2004
Murine interferon‐inducible T‐cell alpha chemoattractant (I‐TAC) is a potent non‐ELR CXC chemokine that predominantly attracts activated T lymphocytes, binds to the receptor CXCR3 and is induced by interferon‐γ (IFN‐γ).
Thomson, SA, Mahalingam, S, Banyer, JL, Ramshaw, IA, Hamilton, NHR   +4 more
core   +1 more source