Results 31 to 40 of about 2,331 (158)
ABSTRACT Background Candida (Candidozyma) auris is an emerging yeast that poses a significant global health threat due to its multidrug resistance and ability to cause healthcare‐associated outbreaks. Genomic surveillance is essential for monitoring spread, transmission and antifungal resistance.
Luiz Marcelo Ribeiro Tomé +19 more
wiley +1 more source
CD8+ T Cell‐Mediated Immunity during Trypanosoma cruzi Infection: A Path for Vaccine Development?
MHC‐restricted CD8+ T cells are important during infection with the intracellular protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease. Experimental studies performed in the past 25 years have elucidated a number of features related to the immune response mediated by these T cells, which are important for establishing the ...
Fernando dos Santos Virgilio +6 more
wiley +1 more source
The Unexpected Actor? Civil‐Military Relations and Regulatory Agency Control in Brazil
ABSTRACT Democratic backsliding around the world has sparked debate about its impact on public administration and governance. This article explores a growing yet less visible phenomenon threatening democracy. It examines the influence exerted by authoritarian populists over autonomous regulatory agencies through militarized patronage, that is, the ...
Bruno Queiroz Cunha +2 more
wiley +1 more source
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi (T. cruzi), is characterized by immunopathology driven by IFN‐γ secreting Th1‐like T cells. T. cruzi has a thick coat of mucin‐like glycoproteins covering its surface, which plays an important role in parasite invasion and host immunomodulation. It has been extensively described that T.
Lúcia Cristina Jamli Abel +8 more
wiley +1 more source
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis +9 more
wiley +1 more source
In earlier studies, we reported that a heterologous prime‐boost regimen using recombinant plasmid DNA followed by replication‐defective adenovirus vector, both containing Trypanosoma cruzi genes encoding trans‐sialidase (TS) and amastigote surface protein (ASP) 2, provided protective immunity against experimental infection with a reticulotropic strain ...
Adriano Fernando Araújo +11 more
wiley +1 more source
Aspectos imunológicos da cárie dentária
O significativo avanço na elaboração de protótipos de vacina contra a cárie é resultado de inúmeras investigações genéticas e moleculares direcionadas aos S. mutans e S. sobrinus e ao mecanismo de resposta imune do hospedeiro.
Leão Pereira PINTO +3 more
doaj +1 more source
Vacinas em saúde pública [PDF]
Vaccines are one of the major triumphs of public health. What may sound like simple common sense has been reiterated in various articles in this Supplement of CSP. At this special moment of mobilization in the fight against the COVID-19 pandemic, the world is placing high expectations on the development of a SARS-CoV-2 vaccine, with many groups working
Luiz Antonio Bastos Camacho +1 more
openaire +3 more sources
Metabolic Profile Associated With Encystation in Acanthamoeba
ABSTRACT The genus Acanthamoeba includes widespread protozoa that can cause severe infections in humans. Their ability to form resistant cysts within infected tissues complicates treatment, making it essential to understand the encystation process for developing effective therapeutic strategies.
Cecília Cirelli +8 more
wiley +1 more source
Cytotoxic Signature and IFN‐γ Production Dominate CD4+ T‐Cell Response During Human Toxoplasmosis
Overview of CD4+ T‐cell subsets in patients with toxoplasmosis. Schematic drawing summarising the most important alterations in CD4+ T‐cell subsets, illustrated in different colours, from patients in distinct stages of toxoplasmosis, represented with different colours, with (lesion) or without (no lesion) ocular manifestations.
Priscilla Miranda Henriques +14 more
wiley +1 more source

