Results 171 to 180 of about 425,388 (212)

Vacuole redevelopment in evacuolated oat protoplasts

, 1992
Hall, J. L., Newell, J. M., Leigh, R. A.
core  

Lewy bodies are surrounded by granulovacuolar degeneration bodies in dementia with Lewy bodies

Brain Pathology, EarlyView.
Here, we report Lewy bodies (LBs) to be enriched for tau‐laden granulovacuolar degeneration bodies (GVBs), suggesting a potential mechanistic interface between α‐synuclein and tau pathology in dementia with Lewy bodies (DLB). Abstract Lewy bodies (LBs), composed primarily of aggregated α‐synuclein (α‐syn), are the pathological hallmark of Lewy body ...
Searlait Thom, Pawel Palmowski, Andrew Porter, Joe O'Neill, Johannes Attems, Laura A. Smith, Viktor I. Korolchuk, Daniel Erskine   +7 more
wiley   +1 more source

An active RNA transport mechanism into plant vacuoles. [PDF]

Nucleic Acids Res
Floyd BE, Liu AY, Venkatesan EA, Wong MM, Morriss SC, Mugume Y, Kazibwe Z, Ridout V, Luo X, MacIntosh GC, Bassham DC.   +10 more
europepmc   +1 more source

A novel myopathy with autophagic vacuoles associated with biallelic variants in CLN8

Brain Pathology, EarlyView.
We describe a novel adult‐onset myopathy with autophagic vacuoles and characteristic features of ceroid lipofuscinosis associated with biallelic CLN8 variants, seizures, and muscle weakness. Autophagosomal/lysosomal deposition of curvilinear, autofluorescent material containing the mitochondrial adenosine triphosphate (ATP) synthase membrane subunit c ...
Ulrika Lindgren, Carola Hedberg‐Oldfors, Kittichate Visuttijai, Sara Nordström, Hans Goebel, Anders Oldfors   +5 more
wiley   +1 more source

The role of ¹⁸F-FDG PET/CT in identifying risk factors for ground-glass nodules in invasive lung adenocarcinoma. [PDF]

Front Med (Lausanne)
Bao W, Ding C, Li N, Huang M, Huang Z, Li H, Fan J, He T, Mao X.   +8 more
europepmc   +1 more source

Ammonia Accumulation Drives Intervertebral Disc Degeneration by Triggering Ammonia‐Induced Cell Death Through Lysosome–Mitochondria Crosstalk

Cell Proliferation, EarlyView.
Mechanical strain disrupts the lysosome‐mitochondria axis via GLS1‐mediated ammonia toxicity, causing NP cell death and ECM breakdown in IVDD. CB839‐mediated GLS1 inhibition effectively rescues cellular homeostasis and alleviates disc degeneration.
Yang Zhang, Yucheng Gao, Shuhang Dong, Shuanggong Liu, Lei Liu, Ziyi Song, Jie Xu, Yijun Rong, Guangxu Song, Yingze Zhang, Dongjin Wu, Zengxin Gao   +11 more
wiley   +1 more source

Coupling of cargo to the autophagy receptor is a critical step in ER-phagy. [PDF]

Sci Adv
Chen S, Banerjee S, Liu D, Kumar K, Obara CJ, Novick P, Prinz WA, Ferro-Novick S.   +7 more
europepmc   +1 more source

Multifocal Epithelioid Hemangioma With FOSB Overexpression

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Epithelioid hemangioma (EH) is a benign vascular tumor that most commonly arises on the skin but may also occur in other anatomical locations, including deep soft tissue, bone, visceral organs, penis, and mucosal sites. A hallmark of EH is overexpression of FOS and FOSB, often resulting from various gene fusions.
Phuong Daniels, Aarush Kumar, Alexa Lum, Izabelle Bermudez, Shannon DeSilva, Jonathan Crane, Kristopher McKay   +6 more
wiley   +1 more source

Divergent Autophagy Pathways in Plasmodium: Mechanisms, Functions, and Therapeutic Potential. [PDF]

Mol Microbiol
Rajput S, Mehra P, Nandi R, Devi R, Pandey E, Varshney A, Mishra S.   +6 more
europepmc   +1 more source