Results 181 to 190 of about 395,932 (267)

Plant Vacuolar and Human Endolysosomal Two-Pore Channels: Similarities and Differences. [PDF]

open access: yesCells
Di Franco E   +9 more
europepmc   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

open access: yesThe FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath   +2 more
wiley   +1 more source

Structural and thermodynamic analyses of a novel β‐1,2‐glucan binding mode in the ABC transporter solute‐binding protein Chy400_4166 from Chloroflexus aurantiacus

open access: yesThe FEBS Journal, EarlyView.
Cyclic β‐1,2‐glucan (CβG)‐associated solute‐binding protein of type I ABC transporter was originally identified in Chloroflexus aurantiacus, a phototrophic bacterium. Crystal structures in complex with CβGs revealed unique binding modes that are fundamentally distinct from that of the short β‐1,2‐glucooligosaccharides‐binding protein.
Kazuya Kato   +6 more
wiley   +1 more source

Characterization of dermatan sulfate and chondroitin sulfate profiles during brain regeneration in Styela plicata

open access: yesThe FEBS Journal, EarlyView.
Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal   +5 more
wiley   +1 more source

Structural insights into θ‐type carbonic anhydrases 3 and 4: Tuning the directionality of CO2 hydration in a diatom

open access: yesThe FEBS Journal, EarlyView.
θ‐CA3 from a marine diatom has an N‐terminal transmembrane helix and two homologous catalytic domains. The enzyme functions as a dimer, with active sites formed near the dimer interface. A bicarbonate ion binds on the symmetry axis of the dimer and forms hydrogen bonds with both monomers, thereby activating θ‐CA3 and tuning CO2 hydration activity ...
Hiroto Negoro   +5 more
wiley   +1 more source

Analysis of the aspartic protease gene family in <i>Nicotiana benthamiana</i> and its application in recombinant protein expression. [PDF]

open access: yesFront Plant Sci
Li Y   +15 more
europepmc   +1 more source

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