Results 291 to 300 of about 438,290 (354)

Autophagy in PE: Dispute, Role and Potential Target

Cell Proliferation, EarlyView.
Autophagy homeostasis serves as a central hub regulating vascular remodelling during pregnancy. It integrates maternal, genetic, and fetal factors; shapes the functions of immune cells (NK cells, macrophages, and T cells); restrains endothelial inflammatory responses (cytokines, endothelial cell, oxidative/ER stress, and protein aggregation); and ...
Miao Xu, Qi Wang, Fang Wang, Li Kang, Huijing Ma, Mengnan Li, Zhuanghui Hao, Zhengrui Li, Ji'an Liu, Xufeng Huang, Hengrui Liu, Shouxin Wei, Hailan Yang   +12 more
wiley   +1 more source

A deep learning-clinical combined model with SHapley Additive exPlanations (SHAP) method for assessing the tumor spread through air spaces in lung adenocarcinoma: a multicohort retrospective study. [PDF]

Quant Imaging Med Surg
Zhang R, Sun JS, Liu ZW, Lin YY, Cai XY, Kang LJ, Guo BL, Song YX, Bao CZ, Chen K, Sun Y, Chen YF, Cai ZP, Xie H, Chen HX, Yang SM, Hu QG.   +16 more
europepmc   +1 more source

A CRISPR‐Cas9‐based system for the dose‐dependent study of DNA double‐strand break sensing and repair

The FEBS Journal, EarlyView.
Using CRISPR‐Cas9, we engineered a genetic system allowing the dose‐dependent induction of a controllable number of DNA double‐strand breaks in Saccharomyces cerevisiae. The tool was used to study the kinetics of DNA break sensing and repair, including the spatial distribution of Tel1ATM kinase, which initiates the DNA damage response.
Morgane Auboiron, Jocelyn Coiffard, Sylvain Kumanski, Olivier Santt, Benjamin Pardo, María Moriel‐Carretero   +5 more
wiley   +1 more source

Characterization of Cd and As accumulation and subcellular distribution in different varieties of perennial ryegrasses. [PDF]

BMC Plant Biol
Cao L, Jiang N, Li B, Deng J, Duan Y, Zu Y, Li Z.   +6 more
europepmc   +1 more source

Primary CD34+ cells of patients with vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK‐243

British Journal of Haematology, EarlyView.
Daniel Nowak, Marie Demmerle, Alessa Klär, Alexander Streuer, Vladimir Riabov, Eva Altrock, Felicitas Rapp, Ann‐Christin Belzer, Teresa Klink, Meret Hahn, Franziska Hofmann, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Melda Göl, Ali Darwich, Laurenz Steiner, Mohammed Abba, Georgia Metzgeroth, Wolf‐Karsten Hofmann, Nanni Schmitt   +21 more
wiley   +1 more source

The Distribution of <i>Neospora caninum</i> Secretory Proteins in Mouse and Calf Brains. [PDF]

Microorganisms
Ushio-Watanabe N, Fujihara R, Watanabe K, Yamada M, Kobayashi Y, Nishikawa Y.   +5 more
europepmc   +1 more source

Different Proteostasis Mechanisms Facilitate the Assembly of Individual Components on the Chitin Synthase 3 Complex at the Endoplasmic Reticulum. [PDF]

J Fungi (Basel)
Sánchez N, Valle R, Roncero C.
europepmc   +1 more source

Polyphosphate Polymerase-A Key Enzyme for the Phosphorus Economy of the Microalgal Cell and the Sustainable Usage of This Nutrient. [PDF]

Plants (Basel)
Solovchenko A.
europepmc   +1 more source

Analysis of the genes and mechanisms responsible for the cytotoxicity of the <i>Legionella</i> Ofk308 strain in the <i>Tetrahymena</i> host. [PDF]

Front Microbiol
Vidayanti IN, Watanabe K, Fujino E, Shimizu T, Watarai M.   +4 more
europepmc   +1 more source