Results 1 to 10 of about 232,600 (377)

The clues offered by SNAREs on the vacuoles of plants and animals [PDF]

Frontiers in Plant Science
Vacuoles and lysosome-related organelles (LROs) are essential compartments in eukaryotic cells playing crucial roles in storage, degradation, signaling, and homeostasis.
Fabrizio Barozzi, Miguel Sampaio, Cláudia Pereira, Gian Pietro Di Sansebastiano   +3 more
doaj   +2 more sources

Intravacuolar persistence in neutrophils facilitates Listeria monocytogenes spread to co-cultured cells [PDF]

mBio
The bacterium Listeria monocytogenes (Lm) causes listeriosis in humans and ruminants. Acute lesions are predominantly infiltrated by polymorphonuclear neutrophils (PMNs), considered to be the efficient bactericidal arm of innate immunity. However, recent
Stefano Bagatella, Camille Monney, Natascha Gross, Véronique Bernier Gosselin, Gertraud Schüpbach-Regula, Andrew Hemphill, Anna Oevermann   +6 more
doaj   +2 more sources

Coxiella burnetii Sterol-Modifying Protein Stmp1 Regulates Cholesterol in the Intracellular Niche

mBio, 2022
Coxiella burnetii replicates in a phagolysosome-like vacuole called the Coxiella-containing vacuole (CCV). While host cholesterol readily traffics to the CCV, cholesterol accumulation leads to CCV acidification and bacterial death.
Tatiana M. Clemente, Rochelle Ratnayake, Dhritiman Samanta, Leonardo Augusto, Paul A. Beare, Robert A. Heinzen, Stacey D. Gilk   +6 more
doaj   +1 more source

Idiosyncratic Biogenesis of Intracellular Pathogens-Containing Vacuoles

Frontiers in Cellular and Infection Microbiology, 2021
While most bacterial species taken up by macrophages are degraded through processing of the bacteria-containing vacuole through the endosomal-lysosomal degradation pathway, intravacuolar pathogens have evolved to evade degradation through the endosomal ...
Bethany Vaughn, Yousef Abu Kwaik, Yousef Abu Kwaik   +2 more
doaj   +1 more source

In Vitro Antioxidant and Anticancer Properties of Various E. senegalensis Extracts

Molecules, 2022
Although Erythrina senegalensis is a plant widely used in traditional medicine in sub-Saharan Africa, its biological properties have been poorly investigated to date.
Souleymane Fofana, Cédric Delporte, Rafaèle Calvo Esposito, Moussa Ouédraogo, Pierre Van Antwerpen, Innocent Pierre Guissou, Rasmané Semdé, Véronique Mathieu   +7 more
doaj   +1 more source

A Phosphoinositide-Binding Protein Acts in the Trafficking Pathway of Hemoglobin in the Malaria Parasite Plasmodium falciparum

mBio, 2022
Phosphoinositide lipids play key roles in a variety of processes in eukaryotic cells, but our understanding of their functions in the malaria parasite Plasmodium falciparum is still very much limited.
Angana Mukherjee, Marie-Ève Crochetière, Audrey Sergerie, Souad Amiar, L. Alexa Thompson, Zeinab Ebrahimzadeh, Dominic Gagnon, Florian Lauruol, Alexandra Bourgeois, Thomas Galaup, Stéphanie Roucheray, Stéphanie Hallée, Prasad K. Padmanabhan, Robert V. Stahelin, Joel B. Dacks, Dave Richard   +15 more
doaj   +1 more source

Antimicrobial peptide LL-37 disrupts plasma membrane and calcium homeostasis in Candida albicans via the Rim101 pathway

Microbiology Spectrum, 2023
Antimicrobial peptides play an important role in human innate defense against microbial pathogens. LL-37 is the only member of the human cathelicidin family of antimicrobial peptides.
Sheng-Yuan Chen, Che-Kang Chang, Chung-Yu Lan   +2 more
doaj   +1 more source

Yeast Morphology Assessment through Automated Image Analysis during Fermentation

Fermentation, 2021
The kinetics and success of an industrial fermentation are dependent upon the health of the microorganism(s) responsible. Saccharomyces sp. are the most commonly used organisms in food and beverage production; consequently, many metrics of yeast health ...
Mario Guadalupe-Daqui, Mandi Chen, Katherine A. Thompson-Witrick, Andrew J. MacIntosh   +3 more
doaj   +1 more source

Gambaran Histopatologi Hepatopankreas Kepiting Bakau (Scylla serrata) di Kawasan Estuari Alue Naga, Banda Aceh Indonesia

Jurnal Sain Veteriner, 2022
The study aimed to investigate the histopathology status of the hepatopancreas of mangrove crabs (Scylla serrata) in the Alue Naga estuary area, Banda Aceh, Indonesia. The research was conducted in September and October 2020.
Dedi Fazriansyah Putra, Nurul Fajar, Cut Dahlia Iskandar   +2 more
doaj   +1 more source

Conditional U1 gene silencing in Toxoplasma gondii [PDF]

, 2015
The functional characterisation of essential genes in apicomplexan parasites, such as Toxoplasma gondii or Plasmodium falciparum, relies on conditional mutagenesis systems. Here we present a novel strategy based on U1 snRNP-mediated gene silencing.
Blackman, Michael J., Das, Sujaan, Gow, Matthew, Heng, Joanne, Jimenez Ruiz, Elena, Meissner, Markus, Melatti, Carmen, Muller, Sylke, Pall, Gurman, Pieperhoff, Manuela, Wong, Eleanor   +10 more
core   +16 more sources